Clarium builds Astra OS, an AI-powered healthcare supply chain resiliency platform that collects, unifies, and automates crowdsourced data from providers, suppliers, and vendors. The platform predicts supply chain disruptions using real-time weather, geopolitical, and current events data and delivers tailored recommendations for substitutions and disruption resolution. Astra OS spans workflow operations, inventory and stock management, and disruption and substitution optimization, and was developed in collaboration with major health systems. Hospitals adopting Astra OS have seen over $10 million in average cost savings, 50% faster disruption resolution, and 88% substitute approvals. Clarium plans to accelerate Astra OS development with additional apps and solutions, expand its team, and grow relationships with new health system partners. The company has expanded leadership and collaborators since its 2024 seed round and has raised $43 million to date. Clarium builds Astra OS, an AI-powered workflow platform and data ecosystem that unifies real-time supply chain data and delivers workflow applications for hospitals. The platform includes modules such as Disruption Monitor, Substitute Manager, and Card Optimizer to automate inventory management and approvals. Since integrating Astra OS, partners have identified an average of $10M+ in cost savings and productivity gains, including a 50% decrease in disruption resolution time, a 63% decrease in substitute approval time, and a 3.7x growth in clinically validated substitutes approved. Yale New Haven Health reports over 300 users across seven departments actively using the platform. The company was founded in 2020 and is headquartered in New York City. Clarium plans to expand integrations, hire across data science, engineering, sales, product, and customer success, and continue investing in generative AI and large language model technologies to augment its offerings.

Total raised

$38M

Funding rounds

2

Latest round

Series A

Latest activity

May 2025