GreenMark is developing regenerative dental products that use patented sub-micron particles produced from food-grade starch to deliver calcium and phosphate for mineral restoration of dentin and enamel. Its lead product line, CrystLCare™ Biorestorative (launched Fluoride-Free first), includes dissolvable sensitivity strips designed to occlude dentinal tubules and restore early-stage caries noninvasively. The company also markets LumiCare™ Caries Detection Rinse and a half-dose LumiKids™ Rinse that use fluorescent-labeled particles to illuminate porous subsurface lesions for early detection. Independent third-party testing cited in the article shows the dissolvable strips can combat dental sensitivity and restore early caries lesions without drilling. GreenMark frames its approach as biomimetic: enzyme-degradable starch carriers release calcium and phosphate to form in-situ apatite crystals, addressing subsurface lesions that some fluoride products only superficially seal. The company emphasizes non-surgical, preventive care to preserve teeth and improve long-term oral health outcomes. GreenMark Biomedical develops nanoparticle‑based dental products that identify and non‑invasively treat early dental "pre‑cavities" using bioresorbable, food‑grade starch particles. Its diagnostic product uses fluorescently labeled starch particles that target active caries and illuminate them with a standard dental curing light; treatment products are designed to load and deliver essential minerals to the enamel subsurface. The company is developing and commercializing its technology in collaboration with researchers at the University of Michigan. GreenMark emphasizes non‑surgical management of early caries to reduce invasive procedures and improve long‑term oral health outcomes. The company operates an office in East Lansing and lab facilities in Ann Arbor, Michigan, and is progressing development alongside multiple state and federal grants and NIH support.

Total raised

$1M

Funding rounds

2

Latest round

Seed

Latest activity

Mar 2019