Siren develops Siren Socks, sensor-embedded socks that continuously measure foot temperature and detect hotspots to identify early signs of diabetic foot ulcers in real time. The company says continuous data collection can reduce DFU risk by up to 68% and amputations by 83%. Siren intends to use new funding to further develop the product and drive clinical adoption. Founder Ran Ma built early prototypes and the startup won TechCrunch’s Hardware Battlefield contest in 2017. Financially, Siren secured $9.5M in the latest strategic round (including an $8M check from Mölnlycke Health Care) and has now raised $43M to date. Past financing includes an $11.8M Series B with backers such as Khosla Ventures. Siren has developed proprietary technology to embed microsensors into fabric, enabling mass production of washable smart textiles. Its first commercial product is an FDA-registered temperature-monitoring sock for early detection of inflammation that can lead to diabetic foot ulcers. The products integrate into users’ everyday lives and provide real-time biofeedback to patients and their doctors. Diabetic foot ulcers cost the U.S. health system over $43 billion annually and lead to more than 100,000 lower-limb amputations, highlighting the market need. To support accelerated product demand, Siren is growing its team and is actively hiring, adding several engineering, sales, and executive hires over the past 12 months. Financially, Siren raised an additional $9M in Series B financing, bringing the total Series B to nearly $21M. Siren develops technology to embed microsensors within fabric to enable mass production of washable smart textiles for remote patient monitoring applications. Its first commercial product is an FDA-registered temperature-monitoring sock that connects wirelessly to a software application. The sock is designed to allow podiatrists to detect early signs of inflammation in patients at risk of developing diabetic foot ulcers. The company has focused on bringing the product to market and positioning itself for commercial expansion. Siren was founded in 2015 and is headquartered in San Francisco, CA. To date it has raised capital across multiple funding rounds to support commercialization. Siren has developed socks built with its Neurofabric technology that embed microsensors to monitor foot temperatures and surface-level changes for people with diabetes. Each sock contains six sensors (12 per pair), is machine-washable and requires no charging. The product is sold via a subscription priced at $19.95 per month, which includes an initial five-pair pack, replacement socks every six months, and access to the Siren Hub for monitoring. The company has iterated several versions of the socks and won TechCrunch’s Hardware Battlefield at CES. Siren plans to create additional health products using the same embedded-sensor approach and says the fabrication process is easily scalable. The company announced a $3.4 million investment from DCM, Khosla Ventures and Founders Fund.

Total raised

$34M

Funding rounds

4

Latest round

Equity

Latest activity

Jan 2025