ImaginAb engineers antibody fragments called minibodies that maintain the specificity of full-length antibodies while remaining inert in the body, enabling PET-based whole-body imaging of immune activity. Its minibodies are used to provide actionable insight into patient selection and treatment progress for cancer immunotherapy. The company is also advancing a CD8 T cell imaging agent designed to non-invasively determine changes in CD8+ T cell tumor infiltrates induced by immuno-oncological treatments. Proceeds from the recent financing will be used to accelerate human clinical trials and to implement centralized manufacturing. ImaginAb raised an additional $8M in equity funding in this round. Martyn Coombs leads the company as CEO. ImaginAb, based in Inglewood, CA, engineers antibodies into smaller protein formats optimized for in vivo molecular imaging. Its pipeline includes imaging agents targeting prostate, pancreatic and ovarian cancer, with IAB2M as its lead program in prostate cancer. The company is co-founded by CEO Dr. Christian Behrenbruch. ImaginAb also maintains roughly 30 collaborations with global pharmaceutical companies across cancer, immune/inflammatory and neurodegenerative targets. The company raised new capital to advance its programs and expand its product pipeline. It intends to use the funds specifically to accelerate development of IAB2M and continue pipeline expansion. ImaginAb develops in vivo imaging agents for Positron Emission Tomography (PET) by re‑engineering antibodies into smaller fragments with fast kinetics while maintaining target biospecificity. The company has over a dozen development programs with global biopharma partners to create companion diagnostic imaging agents for therapeutic antibody drugs, with programs spanning Phase I to BLA. ImaginAb also maintains an internal pipeline of proprietary imaging agents targeting unmet needs, particularly for staging metastatic prostate and pancreatic cancer. The company intends to accelerate clinical development of its cancer and immunology imaging programs using the new financing alongside strategic NCI funding and its expanding pharma companion diagnostics program. Leadership includes CEO Christian Behrenbruch, Ph.D., and founders Drs. Robert Reiter and Anna Wu; the company was founded in 2007 and is based in Los Angeles, CA. The recent financing strengthens resources to advance clinical programs and partner development.

Total raised

$42M

Funding rounds

3

Latest round

Equity

Latest activity

Oct 2017