System is building knowledge infrastructure that shifts decision-making from siloed data to systems thinking. Its core product, the System Graph, is a patented, large-scale statistical graph that models millions of quantitative relationships across disciplines and is updated daily from trusted evidence sources. Today, System’s APIs are already used by leading healthcare providers in the United States and Europe to power clinical decision support systems. The company is committed to open data and open science, guaranteeing free access to its data and promoting systems literacy. With new funding, System plans to release snapshots of the System Graph into the commons beginning in 2026, develop open-source tools for researchers, and convene an annual conference on systems-based solutions. As a Public Benefit Corporation, System has pledged to maintain its mission-driven charter for at least five more years under its latest investment agreement.

Total raised

$19M

Funding rounds

2

Latest round

Equity

Latest activity

Dec 2025