• Gameto

  Participated · Series C · Aug 2025

  Gameto develops stem cell-derived therapies for reproductive health, with its lead program Fertilo using iPSC-derived engineered ovarian support cells to mature eggs outside the body. Fertilo is cleared for commercialization in multiple ex-U.S. jurisdictions (Peru, Mexico, Australia, Japan, India, Singapore, Guatemala, Argentina, Dominican Republic, and Paraguay) and has been used in clinics with five babies born and over 20 pregnancies recorded. The therapy shortens standard ovarian stimulation from about two weeks of daily hormone injections to 2–3 days and is the first iPSC-derived therapy to reach late-stage clinical development in the U.S. Gameto is conducting a randomized, controlled, double-blind Phase 3 trial (FIRST) at up to 20 U.S. sites with an anticipated interim readout in late 2026. Beyond Fertilo, the company is developing the ARPA-H-funded Ameno menopause program, which includes an implantable cell therapy and a next-generation vaginal ring planned for Phase 1. Gameto's platform is built on an AI-powered in vitro organoid system developed with George Church's lab, and the company has raised $127 million to date. Gameto develops Fertilo, a novel investigational in vitro maturation (IVM) solution that uses engineered ovarian support cells (OSCs) to mature eggs outside the body. The company aims to make IVF and egg freezing shorter, safer, and more accessible by reducing hormonal injections. Gameto is led by CEO Dr. Dina Radenkovic and is already using Fertilo in clinical settings in Australia and Latin America. Following discussions with the U.S. Food and Drug Administration, Gameto received tentative approval to proceed to Phase 3 trials subject to completion of certain assay and manufacturing requirements. The recent financing will support clinical development of Fertilo and continued commercial launches in markets where it is in use. Financially, the company reported a $33M Series B that brought total funding to $73M. Gameto is a biotechnology company using cell engineering to develop therapeutics for diseases of the female reproductive system. Its underlying cell‑engineering platform was developed in stealth under a scientific research agreement with George Church’s lab at Harvard Medical School. The company is led by Dr. Dina Radenkovic and operates out of New York City and Madrid. In January it announced three sequenced programs: Fertilo (a biologic for IVF and egg freezing), Deovo (an organoid of the female reproductive system), and Ameno (a cell‑based therapeutic for primary ovarian insufficiency and menopause). Fertilo has entered preclinical development in partnership with clinics in the US and Spain, and partner clinics named include Extend Fertility, RMA, Pozitivf, Ovation Fertility, Clinica Tambre, and Hospital Ruber Internacional. Gameto intends to use the new funding to expand operations and broaden its business reach. Gameto is developing a platform for ovarian therapeutics that targets accelerated ovarian aging to change the trajectory of women’s health and equality. Its initial focus is on addressing menopause and improving assisted fertility through three sequenced programs: Fertilo, Deovo and Ameno. Fertilo aims to improve assisted fertility with a long-term mission to eliminate infertility; Deovo is initiating drug discovery and a computational platform for ovarian aging; Ameno aims to make the medical burden of menopause optional. The company is led by CEO Dr. Dina Radenkovic with Martin Varsavsky as chairman and is based in New York City and Boston, Massachusetts. Financially, Gameto disclosed a $20M Series A and a prior $3M seed (March 2020), totaling $23M in disclosed funding.

• Medal

  Participated · Equity · Jul 2024

  Medal launched Highlight, a capture-based interface and runtime for AI assistants that runs on Windows and macOS and lets users publish web apps as native assistants in under a minute. The platform continuously captures screen context locally (without storing it) and lets users choose from models such as ChatGPT, Perplexity, and Claude, with options to run small models entirely on-device. Highlight exposes open APIs for tasks like meeting transcription and action-item identification and will add additional custom apps soon. The product is built on Medal’s screen-capture and process-detection layer, which is used by over 4 million gamers per month and sits alongside MedalTV’s more than 1 million daily active users. Highlight emphasizes user privacy via opt-in capture, developer control over data routing, and a platform-agnostic approach to encourage competition among AI model providers. With the new funding, the company plans to accelerate development and expand its user base, aiming to become the fastest-growing desktop AI assistant within a year.

• Medal

  Participated · Equity · Jul 2024

  Medal started with a popular video-game clipping product (Medal.tv) and has unveiled Highlight, a cross-platform desktop app that captures on-screen content and supplies that context to LLMs. Highlight runs as a floating desktop button, captures content locally without storing it, and can route context to models such as ChatGPT, Anthropic’s Claude and Perplexity. The company is building its own ChatGPT-like assistant that could eventually run locally and is developing a local transcription app for meetings. Medal raised $13 million at a $333 million valuation from investors including Horizons Ventures, OMERS Ventures, Peak6 and Arcadia Investment Partners. The company will continue supporting Medal.tv while assigning staff to build out Highlight and an open developer platform. Medal is offering developer grants of up to $30,000 and plans to monetize Highlight via an app-store model and a potential premium subscription for local-first models. Medal.tv is a community-focused gaming platform that lets users capture, edit, and share gameplay clips across PC, mobile, and console. The company reports nearly 1 million daily active users, includes more than 1% of content creators on YouTube and Twitch, and its community generates over 2 million clips per day. Medal has expanded its tooling and cloud rendering capabilities through acquisitions of livestreaming platform Rawa.tv and clip/editing tools GifYourGame and Fuze.tv, and launched Medal 3.0 with a Sessions feature for live play, chat, and clipping. The product emphasizes connecting gamers and building shared experiences and communities. Medal plans to use fresh funding to pursue further strategic acquisitions, expand R&D, and hire key talent as it works to become a vertically integrated social network for gaming. Medal.tv provides a clipping and messaging service that enables gamers to capture and share short-form video moments across games. The company is positioning itself as a video-based social network for the gaming generation and as a marketing/discovery tool for game developers. Since launching in February, Medal.tv has amassed 5 million total users and hundreds of thousands of daily active users. The product emphasizes quick shareability over full streaming to lower friction for users and game publishers. Leadership says the $9 million investment will be used to steadily grow the business and further develop interactive social experiences. Management has declined larger offers — saying investors were willing to offer up to $20 million — to avoid taking on what they see as additional risk. Medal.tv provides an in-game clipping tool that captures the last ~15 seconds of gameplay (with optional sound) and is programmed to record only the game via API with opt-in privacy controls. The consumer service is aimed at casual players who share clips on Discord, WhatsApp and Instagram DMs, while Medal.tv also offers a Metrics product that aggregates clip-sharing data for game developers, streamers and esports organizations. The platform supports games such as Apex Legends, Fortnite, Roblox, Minecraft and Oldschool Runescape. The company reports roughly 30,000 weekly users and about 15,000 daily active users; it launched last May and has been growing 5–10% weekly. Founders include CEO Pim DeWitte along with Iggy Harmsen and Josh Lipson; DeWitte previously co-founded SoulSplit. Medal.tv positions itself as enabling shareable game discovery without the complexity of streaming and providing actionable insights for gaming stakeholders.

No current team members are available.