
Connecticut Innovations
865 Brook Street, Rocky Hill, CT, 06067, United States
Overview
[Connecticut Innovations](http://www.ctinnovations.com) provides strategic capital and operational insight to to companies in high-tech industries such as energy, biotechnology, information technology, and photonics. Their mission is to be the leading source of financing and ongoing support for Connecticut’s innovative, growing companies. By offering flexible financing, strategic guidance and introductions to valuable partners, Connecticut innovations enable promising businesses to thrive.
- Total investments
- 191
- Lead investments
- 80
- Investments · 12mo
- 16
- Active investors
- 13
Sector focus
- Biotechnology
- Energy
- Information Technology
- Media and Entertainment
Investment portfolio
- Queen One
Participated · Equity · Aug 2026
Founded in 2022 by CEO Ryan Urban, COO Maricor Resente and Head of Marketing Megan Kresinske, Queen One builds AI-driven software that analyzes shopper behavior to personalize timing, frequency and content of marketing across channels. The platform targets consumer brands—primarily apparel, retail, beauty and home—and the company says it can serve any brand with more than $500,000 in commerce. Queen One reports that its technology has doubled email-generated revenue for some early customers, though it did not disclose customer names or overall revenue. The company employs just under 100 people and has assembled commerce executives and technologists, including veterans from Wunderkind; it raised $5.5 million in early 2025 and has roughly $37.5 million in committed capital, financing and incentives. Queen One has pledged major expansion in Brooklyn—a 30,000-square-foot headquarters backed by up to $6 million in state tax credits and commitments to create 600 jobs by 2030—and says it plans to go public in 2028 under the ticker HEXY.
- Allyx Therapeutics
Led · Equity · Jul 2026
Allyx Therapeutics was founded in 2018 as a spinout from Yale University and is focused on developing therapies for Alzheimer’s disease. Its lead candidate, ALX-001, is preparing to enter a pivotal Phase 2 clinical trial. The company has raised over $60 million in total funding following a recent $26.5 million financing. Allyx is noted as a Connecticut Innovations portfolio company. The recent capital raise is positioned to support the company’s near-term clinical program for ALX-001. Public commentary around the company emphasizes the high unmet need in dementia and Alzheimer’s among older adults.
- Adaptive Insurance
Participated · Equity · Jul 2026
Adaptive Insurance operates as a specialty MGA and insurtech platform offering products aimed at climate- and weather-related exposures. Its offerings include GridProtect, a parametric product for short-duration power outages, a wind and hail deductible buy-back for residential and commercial properties, residential flood insurance with broader coverage and higher limits than the National Flood Insurance Program, and commercial equipment breakdown coverage. The company is developing a proprietary climate intelligence platform to inform its product design and distribution. With the recent $5 million financing, Adaptive has brought total funding to $10 million to date. The new capital is intended to expand its specialty product portfolio and grow its agent and partner distribution network. No revenue, user metrics, founding year, or location were disclosed in the article.
- Rejuvenate Bio
Participated · Equity · Jun 2026
Rejuvenate Bio develops gene therapies aimed at extending healthy lifespan and treating chronic, age-associated diseases by combining advances in gene delivery, translational biology, and longevity science. The company has built a pipeline targeting clinically validated gene targets with a delivery approach designed for well-tolerated, durable expression. Rejuvenate Bio is developing therapies for companion animals with the stated goal of translating insights toward human health applications. The company was founded on research from the Wyss Institute at Harvard Medical School and is headquartered in San Diego, CA. Following the announced $6 million financing, Rejuvenate Bio has also entered a strategic R&D collaboration with Merck Animal Health to advance a targeted animal-health gene therapy program.
- Cypher AI
Participated · Seed · May 2026
Cypher AI is developing an operating-layer service that replaces fragmented, manual systems by unifying experiment design, execution, analysis, and vendor coordination in a single platform. The company works with biotech, pharma, and research organizations to accelerate discovery and innovation across the life sciences. Founded in 2025 by Yaoyu Yang and based in Cambridge, MA, Cypher AI recently closed a $2M Seed round to fund expansion. The company plans to use the proceeds to expand operations and further its development efforts. Early institutional investors in the seed include MaC Venture Capital, Epsilon Ventures, Connecticut Innovations, Sparta Group, and LiquidMetal Ventures. No revenue or user metrics are disclosed in the article.