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K2 HealthVentures

855 Boylston Street, 10th Floor, Boston, MA, 02116, United States

Overview

K2 HealthVentures is an alternative investment firm focused on providing flexible, long-term financing solutions to innovative private and public companies in the life sciences and healthcare industries. The investment team is comprised of collaborative, experienced professionals with diverse backgrounds in finance and operations, as well as deep domain knowledge across various healthcare sectors. A uniquely flexible, permanent capital structure enables the firm to provide creative, adaptive financing solutions and meet the evolving capital needs of its portfolio companies as they grow. K2HV is driven by dual goals of Profit and Purpose – aiming to fuel the growth of innovative companies that will ultimately improve the lives of patients and giving a percentage of investment profits back to underserved areas in healthcare.

Total investments
25
Lead investments
10
Investments · 12mo
5
Active investors
8
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Investment portfolio

  • Hopscotch Primary Care

    Participated · Series D · Aug 2026

    Hopscotch Primary Care operates a technology-enabled primary care model serving rural communities across the southeastern United States. Founded in 2021, the company serves more than 15,000 patients through 12 clinical locations, with its largest concentration in rural Western North Carolina. Its model emphasizes same-day visits, 24/7 access to care teams, and proactive outreach supported by administrative and clinical technology. Hopscotch reports strong patient-facing metrics—Net Promoter Score of 89 and patient retention above 90%—and says it has driven medical-loss-ratio improvement of over 25 percentage points for patients in their first two years. That operating performance is already translating to profitable operations in Western North Carolina. The company plans to use recent funding to expand into additional rural markets and continue scaling its technology-powered operations.

  • Stealth BioTherapeutics

    Participated · Debt Financing · Jul 2026

    Stealth BioTherapeutics focuses on developing therapies that directly address mitochondrial bioenergetic deficits across rare and age-related diseases. The company’s development portfolio includes elamipretide programs in Barth syndrome, polymerase gamma–related mitochondrial disease and dry age-related macular degeneration, a next-generation clinical candidate bevemipretide for ophthalmic and neurological indications, and preclinical assets SBT-255 and SBT-589 for rare mitochondrial disorders. Its parent, Mighty Therapeutics, achieved FDA approval in September 2025 for the first commercial therapy for Barth syndrome and the first FDA-approved therapy to directly target mitochondria, generating revenue from its lead commercial product. The company plans to use newly secured capital to accelerate commercial launch activities and advance late-stage and pipeline development programs. Financially, current cash, cash equivalents and product revenues are expected to extend runway into 2028, with additional financing drawdowns projected to support cash flow positivity in early 2029.

  • Honest Health

    Participated · Equity · Feb 2026

    Founded in 2021, Honest Health partners with hospitals and provider groups to navigate value-based, risk-bearing reimbursement models. Its platform supplies clinicians with actionable analytics, operational support, and shared-accountability structures that prioritize quality and cost containment over volume. Led by CEO Rob Bessler, M.D., and backed by founders from Rubicon Founders, the company combines deep clinical expertise with scalable technology infrastructure. Honest Health’s services include care coordination tools and performance dashboards designed to improve patient outcomes and financial performance for health systems. The company has rapidly gained traction, prompting sizable investor interest. Proceeds from its latest funding will be used to expand into additional U.S. markets, form new partnerships with payers and providers, and further develop its technology and service offerings. No revenue or user metrics were disclosed in the article, but management cites “measurable improvements” in outcomes and cost savings as evidence of early success.

  • Zarminali Health

    Participated · Series A · Jan 2026

    Founded in 2024, Zarminali Pediatrics is building a national multispecialty pediatric health system that unifies primary, specialty, and urgent care under one technology-driven platform. The company currently runs 28 outpatient clinics across eight states and positions itself as a single destination for families seeking comprehensive pediatric services. Its proprietary technology backbone supports coordinated care and alleviates administrative burdens for clinicians, while enhancing access for patients through features such as planned 24/7 telehealth. In 2026, Zarminali intends to open 15 additional de novo clinics in new markets including Chicago, Milwaukee, and Dallas and to broaden its service mix to speech, occupational, and behavioral health therapies. The model emphasizes family-centered design, empowered clinicians, and seamless care coordination. Following its $110 million Series A, the company has raised $150 million in total funding to fuel rapid clinic expansion and technology development.

  • Apella Technology

    Participated · Series B · Jan 2026

    Apella Technology has built an "ambient video intelligence" layer for procedural environments, beginning with the operating room. Its platform uses computer vision and machine learning to automatically detect and label up to 14 surgical case events and then write that data directly into the electronic health record, cutting manual documentation and improving situational awareness. Hospitals deploying Apella report an average 5 % rise in surgical volume as better coordination unlocks capacity and reduces delays. Houston Methodist, a nine-hospital system, expanded from a 36-room pilot to more than 200 operating rooms, illustrating enterprise-scale adoption. The company has also extended its technology to interventional radiology, cardiology and endoscopy suites for broader operational visibility. A new module, Horizon, delivers more accurate case-duration estimates and utilization predictions to optimize scheduling before each day begins. Apella positions itself within the growing "ambient AI" trend in healthcare and was named to Fast Company’s 2025 Most Innovative Companies list.

Team

  • Parag Shah

    Founder, Managing Director & CEO

    LinkedIn
  • Anup Arora

    Founder, Managing Director & CIO

    LinkedIn
  • Nimesh Shah

    Managing Director

    LinkedIn
  • Emily Pettycrew

    Vice President of Finance and Operations

    LinkedIn