
Lewis & Clark Ventures
120 South Central Avenue Suite 1000, St. Louis, MO, 63105, United States
Overview
Lewis & Clark Ventures was founded by former operators with the conviction that innovation and entrepreneurial talent are plentiful in geographies often overlooked. They invest in the highest potential B2B software, fintech, and digital health companies. Their vision is to become a trusted partner to every entrepreneur that they back and assist in their journey towards scale and significance.
- Total investments
- 31
- Lead investments
- 16
- Investments · 12mo
- 0
- Active investors
- 5
Sector focus
- Finance
- Venture Capital
Investment portfolio
- Occuspace
Led · Series A · Mar 2025
Occuspace builds an occupancy intelligence platform for the built environment that uses plug-in WiFi and Bluetooth sensors and proprietary software to deliver real-time, AI-driven space utilization data. The sensors plug into wall outlets to avoid costly installations, and the company emphasizes a 100% anonymous, privacy-first approach. Occuspace serves dozens of Fortune 500 companies and more than 100 colleges and universities, and is expanding its service to higher education, corporate real estate, and government facilities in North America and Europe. Since launching from a university technology competition in 2017, the company has grown rapidly, reporting year-over-year growth of more than 100% since 2021. Occuspace says its data helps facility managers save thousands, if not millions, of dollars by reducing wasted space, improving efficiency, and lowering environmental footprints. The company has raised $14 million to date and positions its product as scalable for massive real estate portfolios. Occuspace is a Los Angeles-based developer of occupancy management technology led by CEO Nic Halverson. It provides an occupancy management solution that helps customers measure and optimize the use of their physical spaces to improve utilization, make informed operational decisions, reduce real estate costs, and enhance visitor experiences. The product features privacy-friendly IoT tracking technology and a consumer iOS and Android app, Waitz, which allow institutions, property owners, and patrons to monitor crowd levels in real time. Customers include UC San Diego, UCLA, Columbia University, Purdue University, Boston College, Baylor University, and others. The company raised $3.6M in Seed funding and plans to use the proceeds to enhance business development and further expand its business reach. Occuspace intends to continue expanding into corporate office, multifamily, travel, government, and retail verticals where it has established product-market fit.
- ArborXR
Participated · Series A · Aug 2024
ArborXR offers a cloud-based platform that lets companies remotely manage AR and VR devices, install apps and content, control user access, and monitor device health in real time. The platform includes a web app for device setup and management, a directory of over 600 app developers, and support for unlimited devices across enterprise and education offerings. ArborXR's education product is used by over 420 educational institutions, and its enterprise service is used by more than 3,000 major companies; the company says its customer base tripled in the last year. The startup supports a wide range of headsets and AR glasses, including Apple Vision Pro, Meta Quest, HTC Vive, Pico, Magic Leap 2, Vuzix, RealWear and others. ArborXR sells subscription tiers (Starter $7/device/month, Essential $10/device/month, Enterprise $13/device/month) and offers a 30-day free trial. The company intends to use new funding to develop and scale the platform to meet growing demand and advance its long-term vision of XR transforming learning and work.
- Sailes
Led · Series A · Sep 2023
Sailes is an AI company based in Kansas City, MO and New York City that builds patent-pending Sailebots and proprietary standalone infrastructure to automate all points in the prospecting lifecycle. The product deploys globally compliant, personalized AI agents to multiply enterprise sales reps and complete prospecting activities. The company reports adoption from Fortune 500 customers across commercial sectors including real estate, heavy equipment, financial services, environmental, social, and corporate governance, and manufacturing. Led by CEO and founder Nick Smith, Sailes positions its offering as sales with AI for enterprises rather than simple enablement. The company intends to use new funding to expand operations and broaden its business reach. Financial specifics in the article note a recent Series A plus total funding to date. Saile.ai provides a SaaS AI solution that automates the entire prospecting life cycle with Sailebots that perform Digital Labor sales tasks for mid-market and global enterprise businesses. Co-founded by enterprise sales veteran Nick Smith and technologist Clive Cadogan, MsC, the company serves Fortune 500 customers including Schneider Electric, LPL Financial Services, Finning Caterpillar, JLL Commercial Real Estate, and BrandSafway group. The company is based in Kansas City, MO and maintains offices in New York. Saile.ai intends to use recent funds to continue to expand operations and its business reach. The company raised seed financing in late 2022 as part of its current funding status.
- Dalia
Led · Series A · Jan 2023
Dalia offers a recruitment marketing automation platform that integrates with employers’ existing ATS and CRM systems to capture and convert job-seeker traffic that would otherwise be lost. The fully automated solution aims to generate more qualified applicants while lowering job-advertising spend, and can be deployed within days. Current mid-market and enterprise customers include Compass Group, Ryder, Valvoline, Brink’s, Baptist Health South Florida, and PeopleReady. Led by CEO Sam Fitzroy and COO Jason Whitman, the company plans to use newly raised capital to broaden its product suite focused on maximizing career-site conversion rates. Additional spending will be directed toward scaling sales and marketing efforts. Dalia positions itself as the preferred recruitment marketing automation provider for large employers, leveraging its roster of well-known clients to drive adoption. No revenue, user count, or other operating metrics were disclosed in the article. Based in New York City, the company is targeting continued growth within enterprise talent-acquisition teams.
- PayGround
Led · Equity · Jul 2022
PayGround provides a healthcare payments platform and mobile app that lets patients manage, track and pay all medical bills in one secure place. The platform is designed to modernize payments for providers by reducing costs, simplifying processes and boosting patient and employer satisfaction. Led by CEO Drew Mercer, the company has entered the ambulatory market and is positioning to expand into hospitals and health systems. PayGround raised a $19.7M Series A to support that expansion and to grow its senior leadership team. The product targets both patient-facing convenience and operational efficiencies for medical providers. No operating metrics (revenue/users) were disclosed in the article. PayGround is a healthcare fintech payments platform based in Gilbert, AZ, led by CEO Drew Mercer. The company’s mobile app lets patients take a picture of a bill, select a payment method and click pay to settle bills from all providers in one place. PayGround also streamlines the collections process for healthcare providers. The company closed a $5.5M funding round to support its growth. Management says the proceeds will be used to expand into new markets, invest in new marketing campaigns and enhance the platform’s features. No other operating metrics or past financings were disclosed in the article. PayGround builds an integrated healthcare payments engine that lets patients submit payments to all their providers through one workflow and user interface. For providers, the platform centralizes payments and improves collections and revenue-cycle economics. Founded in 2018 and based in Gilbert, Arizona, PayGround has deployed in over 100 healthcare facilities within a year of commercial market presence. Providers using PayGround have experienced an average 23% increase in revenue, more than a 60% decrease in collections turnaround time, and over 40% savings versus prior vendor fees. The company plans to use new funding to execute its technology roadmap and pursue an aggressive sales and marketing plan. PayGround has also expanded its board with investor representatives and healthcare IT leader Dan Johnson.