UpSurgeOn builds a “hybrid” simulation ecosystem that combines physical, hyper-realistic anatomical models with virtual reality and digital platforms to provide standardized surgical training environments. Its platforms measure surgical skills against objective data to improve patient safety and reduce learning curves for complex procedures. The company has commercialized its technology in over 110 countries and collaborates with major global medtech companies and scientific institutions. Current multidisciplinary applications include cranial and spinal neurosurgery and plastic surgery, and the firm plans to expand into specialties such as orthopedics and ENT. UpSurgeOn is led by CEO and co-founder Federico Nicolosi and has secured over €8M in total institutional funding following the latest €5M round.

Total raised

$6M

Funding rounds

1

Latest round

Equity

Latest activity

Mar 2026