Aphelion/Cardeation Capital
100 Tiburon Boulevard Suite 215, Mill Valley, California, 94941, United States
Overview
A collaborative venture capital fund designed to spur healthcare innovation in heart disease and stroke care.
- Total investments
- 2
- Lead investments
- 0
- Investments · 12mo
- 0
- Active investors
- 0
Sector focus
- Financial Services
- Health Care
Investment portfolio
- Laplace Interventional
Participated · Series C · Mar 2025
Laplace Interventional is a Minnesota-based medical device company developing a prosthetic transcatheter tricuspid valve delivered via a minimally invasive procedure to avoid open-heart surgery. The device is intended to improve quality of life for patients with tricuspid regurgitation. The company has completed an Early Feasibility Study (EFS) experience treating three patients (all discharged home within 1–2 days) and has enrolled 22 patients in the U.S. EFS and 25 patients globally. Laplace announced a $22M Series C financing to support completion of its U.S. and OUS feasibility studies and to work toward initiating a pivotal study. The company added Ned Scheetz of Aphelion Capital to its board as part of the financing announcement. The device remains in development and is not approved or cleared by the FDA or any other regulatory body. Laplace Interventional is a Minneapolis, MN–based medical device company developing a transcatheter prosthetic valve system to treat patients with tricuspid regurgitation. The device is designed to be delivered through patient vasculature, avoiding open‑heart surgery and aiming to increase life expectancy and improve quality of life for patients with TR. The technology is in an early stage of development and is not approved or cleared by the FDA or other regulatory bodies. The company intends to use the new capital to pursue first‑in‑human (FIH) and clinical feasibility evaluations of its valve system. Ramji Iyer is founder and CEO, and the company has recently added industry executives to its board, including Jenny Barba and Todd Mortier. Laplace Interventional is a Minnesota-based medical device company developing a transcatheter tricuspid valve technology. Its core product is a prosthetic valve designed for minimally invasive delivery that avoids open-heart surgery to treat tricuspid regurgitation. The company says the device aims to increase life expectancy and improve quality of life for patients with TR. Laplace recently closed a $7.9M Series A to fund progress toward preclinical milestones. Leadership added two directors to the board, including William Dai of ShangBay Capital, a participant in the round. The device remains in early-stage development and is not approved or cleared by the FDA or other regulatory bodies.
- MIVI Neuroscience
Participated · Series B · Jan 2021
Mivi Neuroscience is an Eden Prairie, Minn.-based medical device company focused on improving clinical outcomes for ischemic stroke patients. It develops and commercializes neurointerventional devices, including its two flagship products, the Q™ Aspiration System and the DAISe™ Thrombectomy System. Its product portfolio is designed to reduce complications, shorten procedure times and expand treatment to more patients. The company closed a $35M Series B in new money plus the conversion of previously issued convertible notes to fund clinical trials and subsequent commercialization. Proceeds will also support expansion of commercial operations outside the United States and the development of several innovative devices to support and enhance its products. The company is led by CEO Bob Colloton. MIVI Neuroscience develops medical devices for neuro-interventional procedures, with a product portfolio designed to improve outcomes and shorten procedure times. Its tools aim to enable easier access to smaller, difficult-to-treat cerebral vessels and potentially expand treatment to more patients. The company’s devices are positioned for endovascular stroke therapy, a field that has seen significant global growth since pivotal clinical trials in 2015–2016. MIVI aims to make treatment available to more patients by providing access to smaller vessels in the brain. The article reports that Concord Health Partners has completed an investment in MIVI, reflecting investor interest in its proprietary technologies that may lower costs and enhance the value of care.
Team
No current team members are available.