Builders VC
601 California Street Suite 700, San Francisco, CA, 94108, United States
Overview
Builders VC is an early-stage venture capital firm focused on investing where technology meets new business models to modernize antiquated industries including healthcare, agriculture, industrials and real-estate.
- Total investments
- 67
- Lead investments
- 29
- Investments · 12mo
- 10
- Active investors
- 8
Sector focus
- Financial Services
- Venture Capital
Investment portfolio
- Colossal Biosciences
Participated · Equity · Aug 2026
Colossal Biosciences focuses on applying AI to biological questions, including predicting how biological systems fail or break. The company is co-founded by Ben Lamm and has been associated publicly with figures such as George Church, Beth Shapiro, and Adam Milne. Financially, Colossal announced a $20 million financing at a $3.8 billion valuation. The recent capital raise is described as supporting its AI initiatives. The provided articles do not include revenue, user, or other operating metrics, nor do they state the company's founding year or location.
- Astromech
Participated · Equity · Aug 2026
Founded in September 2025 by Ben Lamm and George Church, Astromech trains AI on genomic data provided by Colossal to predict changes, vulnerabilities, and regulatory variation in living systems. Its first public project compares longevity- and cancer-related biology across species such as cancer-resistant Asian elephants, 200-year-old bowhead whales, and long-lived Brandt’s bats against shorter-lived relatives. The company reports having mapped 46 genes linked to cellular maintenance, cancer resistance, and longevity. Astromech positions its platform earlier in the discovery pipeline than many peers by forecasting where biological systems may fail before drug targets are identified. Competitors noted in coverage include Insitro and Isomorphic Labs, which operate in adjacent machine-learning-driven biology and drug-discovery spaces. Financially, the company has raised $60 million to date and now carries a reported valuation of $3.8 billion.
- Ranchbot
Participated · Series B · Aug 2026
Ranchbot combines field-installed hardware with recurring software to allow producers to remotely monitor water infrastructure and other assets across large agricultural properties. Water management remains the company's foundation, but it is developing broader capabilities that are expected to encompass livestock, wildlife and natural capital such as soil, pasture and biodiversity, plus other ranch and farm infrastructure. The company serves more than 12,000 customers responsible for roughly 10 million cattle and 15 million sheep across Australia, North America and other markets. With the Series B financing and a new global holding structure based in Fort Worth, Ranchbot is investing in additional staff, hardware and software development and pursuing partnerships to expand its platform. It is positioning its data infrastructure for potential value beyond individual farms, including use cases for insurers, lenders and supply-chain companies.
- Farmbot
Participated · Series B · Aug 2026
Founded in 2014, Farmbot builds satellite-connected sensors and a software platform that lets farmers monitor tanks, troughs, dams, pumps and rainfall remotely. The company serves more than 12,000 customers across Australia, North America and other markets and reports management of about 10 million cattle and 15 million sheep. It operates as Ranchbot in the U.S. and is now headquartered in Fort Worth, Texas. With the recent $22 million Series B, Farmbot plans a corporate reorganization to establish Ranchbot Technology Holdings Inc. as the global parent, hire additional staff, and continue improving its hardware and software. Leadership has indicated plans to evolve the product offering into broader agricultural and water management solutions for the farm sector.
- Askari
Led · Seed · Jun 2026
Askari develops hand‑launched, fully autonomous hit‑to‑kill interceptors designed for dismounted operators; its two main systems are Rift Alpha and Rift Bravo. Rift Alpha targets Group 1 and 2 UAS, can be launched from the hand, a tube, or a box, has a range of about 2 km and top speed around 60 m/s, and is already in customer use. Rift Bravo is a smaller, foldable Group 1 interceptor with roughly 1 km range, speeds above 100 mph, and a form factor that allows a dozen to fit in a rucksack; Bravo remains in development supported by non‑dilutive R&D contracts. Askari says it has over $2M in real procurement contracts and an order book exceeding $2M, with customers predominantly in the special operations community and reported intercept rates near 90% during testing with a Tier One customer. The company emerged from stealth in April, was founded by Georgia Tech alumni Robbie Van Zyl and Ben Airdo (both 25) alongside Marc Van Zyl, and plans to use new funding to scale production and expand engineering and operations headcount. Future product ambitions include adapting interceptors for ground‑vehicle threats and developing tooling to automate rapid interceptor design and delivery.