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The Venture Codex

Chemistry

421 Bryant Street, San Francisco, CA, 94107, United States

Overview

Chemistry VC is a venture capital firm that focuses on seed and Series A investments in innovative startups. The company leverages institutional experience to support founders in scaling their businesses effectively.

Total investments
15
Lead investments
6
Investments · 12mo
12
Active investors
3

Sector focus

  • Finance
  • Financial Services
  • Venture Capital
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Investment portfolio

  • Meticulous

    Led · Series A · Jul 2026

    Meticulous builds an AI-driven platform that records application interactions during development and automatically generates and maintains end-to-end tests covering user workflows and edge cases. The system compares application behavior before and after code changes to identify potential issues and help developers assess impact prior to release. Founded in 2021 by brothers Gabriel and Quentin Spencer-Harper, the company currently focuses on frontend testing with plans to expand into backend and performance testing. Meticulous recently raised $15 million in a Series A led by Chemistry to fund engineering hires and product development.

  • Assort Health

    Participated · Series C · Jun 2026

    Assort Health operates a unified platform of AI agents for the patient journey, spanning concierge call handling, proactive patient outreach, operational orchestration that writes back to EHRs, and staff-facing AI copilots. Its proprietary model, Synapse, is trained on more than 190 million patient interactions, 62,000 care protocols, and 1.6 million decision pathways to handle specialty workflows and edge cases. Customers reportedly see a 5% lift in appointment volume, a 115% increase in labor capacity, and a 4.3 out of 5 patient satisfaction score. The platform integrates with major EHR and practice management systems including Epic and Athena to enable deployments without disrupting clinical workflows. Assort has expanded into large health system operations and says revenue has grown 20x in the past 15 months as it scales deployments nationwide.

  • Nova

    Led · Series A · May 2026

    Nova develops agentic AI that automates complex, mission-critical SAP workflows, beginning with the S/4HANA migration wave. The company positions migration as an initial wedge into a larger opportunity spanning development, testing, documentation, modernization, production issue resolution, and daily operations for SAP customers. Coverage highlights significant early traction and investor interest, with a seed led by Accel and Position Ventures as an early backer. Nova announced a $31.5 million Series A led by Chemistry to accelerate product deployment and customer adoption. Leadership cited in reporting includes Emma Qian, Sam Yang, and Prof. Dr. Alexander Zeier. Public statements emphasize targeting enterprises undergoing large-scale SAP modernization to reduce technical debt and avoid business disruption.

  • Fathom Therapeutics

    Participated · Series A · Apr 2026

    Fathom Therapeutics develops Microcosmos, a drug design engine that uses proprietary physics-based algorithms and AI to simulate protein dynamics at atomic resolution and enable generative design of small molecules. The platform reportedly accelerates modeling of protein dynamics by 10,000x without compromising accuracy and produces data intended to translate quantum mechanical calculations to measurable cellular outcomes. Microcosmos has guided discovery and optimization across multiple target classes and modalities, including rapid generation of novel degraders that are being optimized for clinical advancement. Fathom has an active internal pipeline, multiple external discovery partnerships, and its lead program has progressed into animal efficacy studies. The company was founded by researchers behind the Anton supercomputer and widely used protein–drug binding software, and its leadership team has collectively advanced 19 drugs to the clinic, including seven FDA-approved medicines. Fathom is headquartered in New York and maintains a second office in Boston.

  • ComfyUI

    Participated · Equity · Apr 2026

    Founded as an open-source project in 2023, ComfyUI developed a modular, node-based interface that lets creators control each step of generation from diffusion models for image, video, and audio. The tool has been adopted by creative professionals and technical artists, with the company reporting over 4 million users and usage across visual effects, animation, advertising, and industrial design. ComfyUI evolved from a community project into a formal startup and has raised multiple rounds, including $19 million in a late‑2024 Series A and the recent $30 million round at a $500 million valuation. Yoland Yan is the company’s co-founder and CEO and has emphasized the platform’s role in enabling precise, human-in-the-loop adjustments that prompting alone often cannot deliver. The company faces competitors in adjacent tooling, including Weavy, which was acquired by Figma.

Team