Participated · Equity · May 2026

MSICS Pharma develops and manufactures GMP-grade psilocybin and markets a flagship product, MSX-06, intended for integration within medical treatment protocols. The company holds the only Ministry of Health license in Israel and Europe for GMP psilocybin production for medical use. MSICS is conducting Phase II trials for treatment-resistant depression and OCD and is preparing a large multi-center PTSD trial with four Israeli hospitals while awaiting approval to treat 100 PTSD patients. Internal study results have reportedly shown up to 70% full remission in depression in some cases. The company was founded and is led by brothers Roei Zerahia (CEO) and Omer Zerahia (CBO), who previously led Canndoc. MSICS employs about 12 people and plans to use recent funding to expand production, speed its clinical program, and pursue commercial registration and global supply.

Participated · Seed · Oct 2023

Treetscope provides a plant-based irrigation management platform that uses in-tree/plant sensors to directly measure real-time sap and water uptake, rather than relying on soil or trunk-only sensors. Its system combines those plant measurements with AI, integrated weather data, satellite imagery and other remote data to generate more accurate irrigation schedules. The platform is designed to help growers cut water and other input costs while maintaining optimal crop health and production. The company has commercial collaborations with The Toro Company (co-branded Transpira, enabling sales in the U.S. and Mexico) and a three-year validation with Netafim that supports global commercialization. Treetscope is led by CEO Dotan Eshet and is based in Tel Aviv, Israel. Financially, the company recently closed a $7M Seed round and has secured more than $10M in total investments to date, including grants from the Israel Innovation Authority and the Binational (Bird) Foundation.

Participated · Series B · Dec 2021

Cylus builds CylusOne, a rail cybersecurity platform that offers continuous monitoring and 360-degree real-time protection for mainline and urban railway systems. The platform enables real-time threat detection, advanced forensics, mitigation, and simplified security operations while integrating with new and legacy systems without network-architecture changes. CylusOne installs in a few hours with zero downtime and claims full visibility within seconds. The company announced a $30M Series B and said total funding now exceeds $57M; it did not disclose a post-money valuation. Cylus plans to use the capital to expand globally across North America, Europe and the Asia Pacific and to hire specialists in cybersecurity, traffic management and onboard/trackside systems. The company also intends to strengthen its AI and machine learning capabilities and has announced a strategic partnership with Alstom to protect the Tel-Aviv red line’s signaling and train control systems. Cylus is an Israel-based company founded in 2017 that develops cybersecurity solutions tailored to the railway sector. Its flagship product, CylusOne, is designed for the diversity and complexity of rail and metro environments and protects signalling, control, communications, trackside and onboard systems. CylusOne uses machine learning to speed detection of malware and artificial intelligence to determine behaviour and handle responses. The system is compatible with CBTC and ETCS and is intended for both mainline and urban networks to maximize performance, capacity and availability. Cylus entered a commercial partnership with Alstom, which invested US$7 million for a minority stake and will take one board seat; the technology is slated for initial implementation on the Tel Aviv metropolitan light rail system serving about 200,000 passengers a day. The partnership aims to integrate cybersecurity into rail processes and solutions globally and to help drive cyber-resilience standards for mobility. Cylus is a Tel Aviv-based company that develops cybersecurity solutions for railways and metro operators. Its core product, CylusOne, detects threats across signalling and control networks, as well as trackside and onboard systems, enabling timely responses before harm occurs. The company says rail systems have become technologically advanced and face growing cyberattack threats. Cylus reports established relationships with key players in the rail industry and growing partnerships with leading rail operators. Financially, Cylus secured $12 million in its latest funding round from Cyient, Cerca Partners, GlenRock, and FollowTheSeed, bringing total funding to $17 million to date. Cylus develops a platform that enables rail companies to detect cyber-attacks in their operational networks, including signaling systems and rolling stock, and to block attackers before they can cause damage. Key platform features include enhanced security that preserves existing safety mechanisms, centralized operational visibility through a unique interface that makes trackside and trainborne devices visible to operators, multi-vendor integrated systems protection to identify weak links, and preemptive threat response. The company targets railways and metros and is led by CEO Amir Levintal, formerly director of the IDF Cyber R&D Division; Boaz Zafrir serves as president and is a former CEO of Israel Railways. Cylus was founded in 2017 by veterans of the Israeli Defense Forces' Intelligence Corps' technological intelligence and security units. As of January 2018 the company raised $4.7M in seed funding from investors including Zohar Zisapel, Magma Venture Partners, Vertex Ventures and the SBI Group. The platform's focus on safety-integrated cybersecurity and multi-vendor support positions it to serve operators seeking centralized visibility and proactive defense.

Participated · Series B · Dec 2021

Karamba Security builds security products and services that protect IoT devices and connected vehicles throughout the device lifecycle without disrupting R&D or supply-chain processes. The company recently launched a cloud-based incident analysis service to complement its offerings. Karamba says it has 80 successful engagements with Fortune 500 companies and one engagement that secured a fleet of 800,000 units across more than 100 countries. Management emphasizes strong regulatory demand driving adoption among IoT manufacturers and automotive OEMs. Financially, this fundraising news brings the company’s total funding to $27 million. The company continues to target automotive and IoT OEMs seeking seamless, lifecycle security. Karamba Security provides industry-leading automotive cybersecurity software, including products such as Carwall and SafeCAN, that protect endpoints and the internal messaging bus. Its solutions prevent cyberattacks with zero false positives and secure communications, including OTA updates, while adding negligible performance overhead. The company’s software is integrated across chip architectures (ARM, Intel, PowerPC, Infineon) and OS/scheduler platforms (QNX, Linux, various RTOS and AUTOSAR). In the two years following its launch, Karamba has engaged with 17 automotive OEMs and tier‑1 suppliers. Karamba plans to use new funding for inorganic growth, including acquiring companies and technology assets to accelerate its Autonomous Security portfolio and meet growing demand from automotive and IoT customers. Financially, its operations were funded by a $17M raise last year and it recently added a $10M venture debt facility, bringing total investment to $27M. Karamba Security builds embedded security software installed in a vehicle’s electronic control units (ECUs) that locks down factory settings and prevents execution of programs that deviate from those settings. The company’s approach is built-in rather than relying on PC-style intrusion detection, aiming to stop malevolent hacks on embedded automotive systems. Karamba has worked with 16 new customers in the past 15 months in the cost-sensitive automotive manufacturing industry. Co-founder and chairman David Barzilai says the product is installed inside ECUs that control brakes, navigation and entertainment. The company will use new funding primarily for hiring, continued R&D, performance testing and to open offices in Michigan near major U.S. automakers. To date Karamba has raised $17 million across three rounds within about one year. Karamba Security develops the Carwall Autonomous Security suite, software that automatically locks down vehicle ECUs to factory-known instructions so they can block unauthorized operations locally. The product extension includes in-memory protection that blocks memory-based attacks such as buffer overruns and return-oriented programming (ROP). Karamba emphasizes deterministic, on-ECU decisions that require no connectivity, no anti-malware updates, and impose a negligible CPU/performance footprint. The company claims its approach yields zero false positives, avoiding the safety risks associated with network-based detection. Five months after emerging from stealth, Karamba completed proof-of-concept work with several Tier-1 suppliers and reports strong demand from OEMs and Tier-1 providers; FEV North America is cited as integrating Carwall into its reference platform. The company is actively promoting its Autonomous Security framework at multiple industry events this fall. Karamba Security builds cybersecurity software that is installed on vehicle controllers (ECUs) to lock factory settings and prevent foreign code or banned behaviors from running, thereby blocking access to a car's CAN Bus. The software can be deployed as a retrofit or preinstalled on controllers for new vehicles. Karamba aims to protect both infotainment and critical vehicle systems such as braking and fuel injection. The company emerged from stealth and operates from Tel Aviv with a business development office in Detroit. Co-founders include Ami Dotan, Tal Ben-David, David Barzilai and Assaf Hare. Karamba closed a $2.5 million seed round in March and plans to use the funds for hiring, research and development, and to lock in early customers, with the expectation of signing full-year contracts with major automotive suppliers next year.

Participated · Series A · May 2021

Lydus Medical, based in Ra’anana, Israel, develops a novel product line to automate creation of small blood vessel anastomoses. Its lead product, the Vesseal, enables precise, symmetrical and rapid connection of blood and lymph vessels from 4.0 to 0.5mm for procedures including breast reconstruction, lymphedema treatment, bypass surgery and hemodialysis access. The company’s pipeline includes a diverse portfolio of products all based on a patented invention. Led by CEO Jessica Weiss, Lydus plans to use the funding to accelerate FDA clearance, scale product development and prepare for market entry. The company raised $2.7m in a Pre-A funding round.