
JumpStart Ventures
330 N Wabash Ave, Suite 2500, Chicago, IL, 60611, United States
Overview
JumpStart Ventures is an investment fund built to partner with entrepreneurs solving problems that need intelligent innovation and ambitious solutions.The fund invests in founders with humble invincibility and purposeful creativity launching companies that positively impact the world around them.
- Total investments
- 34
- Lead investments
- 15
- Investments · 12mo
- 2
- Active investors
- 3
Sector focus
- Enterprise Software
- Financial Services
Investment portfolio
- Folio Photonics
Participated · Series A · Jun 2026
Folio Photonics designs multilayer optical discs that store data as fluorescent signals in a nanophotonic optical medium, producing WORM (write-once, read-many) discs with expected lifetimes of 50–100 years. Its discs can contain up to 32 layers with an estimated storage cost from $3 per terabyte; first-generation discs hold about 1–2 TB each and multiple discs can be housed in a single cartridge. The company has patented its core technology, built an alpha optical drive in 2024 and a second-generation beta last year, and hired an engineering manager three years ago to advance drive development. Folio plans commercial launch in 2027 and aims for integration with existing manufacturing ecosystems to speed adoption. The company positions its product as an archival and “knowledge layer” for AI-era data preservation and cites a forecasted archive market exceeding $12 billion by 2028. Financially, Folio has completed multiple funding events including a 2019 $8M seed round and a recent Series A of $8M, and intends to use new proceeds to scale engineering, operations, partnerships and manufacturing readiness.
- Ethermed
Participated · Series A · Apr 2026
Ethermed provides an intelligent automation platform that uses advanced language models and clinical reasoning to review documentation, interpret payer rules, and generate compliant prior-authorization submissions in seconds. The platform integrates with EHRs and payer systems and has processed millions of prior-authorization transactions. Ethermed reports a growing customer base, including nine customers prior to the Series A, and measurable reductions in denials and staff workload. CEO and co-founder Dan Friedman emphasizes amplifying clinical judgment through automation that understands medicine. The company plans to expand its data science and engineering teams and deepen partnerships with national health systems. Ethermed positions its technology to reduce administrative burden, improve accuracy, and speed access to care.
- orthobrain
Led · Equity · Apr 2025
orthobrain provides a total orthodontic practice-growth system combining proprietary digital technology, AI-driven learning systems, and expert orthodontic mentorship to enable general practitioners to deliver orthodontic care. Its offerings include clinical workflow tools, educational resources through orthobrain University, and SimplyClear™, a proprietary clear aligner system launched in 2022 designed for dentists. The company is rolling out an enhanced technology platform to streamline clinical workflows and optimize treatment outcomes. Funding will support team expansion, technology enhancements, marketing, and educational initiatives to expand provider access. orthobrain reports strong commercial traction: revenue grew 145% year-over-year and doctor registrations surged more than 185% since 2023. The company emphasizes enabling case selection, treatment planning, and ongoing orthodontic guidance to drive practice profitability and patient retention. orthobrain is a dental practice growth system that integrates orthodontics into general practices using digital technology, proprietary AI, learning systems and the expertise of orthodontists. Founded in 2016 by Dr. Dan German and based in Cleveland, Ohio, the company positions itself as a proven integration platform for orthodontic services. In July 2022 orthobrain completed a $9M Series A financing. The company intends to use the funds to expand access to quality orthodontic care globally and to scale clinical and education support services. orthobrain also plans to invest in technological solutions and continue innovating its product and service offerings. The description of its core product emphasizes combining technology, AI and orthodontist expertise to drive practice growth.
- LunchTable
Led · Seed · Jul 2024
LunchTable (formerly Inphlu) operates a brand amplification platform focused on deepening connections between fans and sports teams through gamification, exclusive content, and two-way interaction. The platform aims to convert passive spectators into passionate social media advocates while delivering targeted exposure for sponsors and actionable data insights. LunchTable has completed pilot partnerships with the Cincinnati Reds, FC Cincinnati, the University of Toledo, and the University of Cincinnati. The company announced a strategic rebrand to LunchTable to emphasize community and fan engagement. With the new funding, LunchTable plans to expand its sales and marketing team, refine the platform, and build a robust customer support infrastructure ahead of a planned commercial launch within the next six months.
- OnStation
Led · Series A · Jun 2024
OnStation is a Cleveland, OH-based provider of a collaborative digital stationing platform tailored to the heavy highway industry. Its mobile app centralizes communication and delivers location-based project records from bid to close, with instant jobsite stationing, milepost, and LRS capabilities. Users can overlay design layers on project maps and communicate via a custom chat platform that organizes and records project events at their locations. The platform is designed to boost productivity, enhance worker safety, and improve project quality across civil engineering and roadway projects. OnStation is available on the Apple App Store and Google Play and is supported on desktop systems. The company intends to use the newly raised funds to accelerate growth, expand its customer base, and enhance its platform. OnStation is a mobile application that enables better communication, location-based documentation, and streamlined issue tracking for road construction projects. The app serves as a complementary plugin to larger road construction tech solutions and provides access to project design files and contract documents. It is currently in use in 23 states and reports its customer base grew seven-fold over the past seven months. OnStation plans to use new funding to scale nationally, hire sales professionals and additional developers, and automate the project onboarding process. Leadership credits JumpStart Cleveland for four years of mentorship and support, and the product was built by founder and CTO Jake Bailosky based on his experience at the Ohio Department of Transportation. The company intends to add functionality and grow headcount to meet anticipated demand if federal infrastructure funding increases roadway projects.