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Lightstone Ventures

2884 Sand Hill Road, Suite 121, Menlo Park, CA, 94025, United States

Overview

Global venture capital firm investing in personalized medicines.

Founded

2012

Deals ยท 12mo

3

Links

WebsiteLinkedInX (Twitter)

Stage focus

Series A
Series B
Series C

Geographic focus

Ireland
United States

Sector focus

Finance
Financial Services
Health Care
Precision Medicine
...

Investment portfolio

63rounds
NAMEDATESIZE
Crystalys Therapeutics
Jul 2026Participated
$130 MSeries B
Cerevance
May 2026Participated
$20 MSeries C
PsiThera
Dec 2025Led
$48 MSeries A
Crystalys Therapeutics
Sep 2025Participated
$205 MSeries A
Alchemab Therapeutics
Sep 2025Participated
$32 MSeries A
ProVerum
Aug 2025Participated
$80 MSeries B
Reprieve Cardiovascular
Aug 2025Participated
$61 MSeries B
Apreo Health
Aug 2025Participated
$130 MSeries B
Allay Therapeutics
Jun 2025Led
$58 MSeries D
Atsena Therapeutics
Apr 2025Participated
$150 MSeries C
FIRE1
Jan 2025Participated
$120 MOther Equity
Amber Therapeutics
Jun 2024Participated
$102 MSeries A
Crystalys Therapeutics
Jul 2026Participated
$130 MSeries B
Cerevance
May 2026Participated
$20 MSeries C
PsiThera
Dec 2025Led
$48 MSeries A
Crystalys Therapeutics
Sep 2025Participated
$205 MSeries A
Alchemab Therapeutics
Sep 2025Participated
$32 MSeries A
ProVerum
Aug 2025Participated
$80 MSeries B
Reprieve Cardiovascular
Aug 2025Participated
$61 MSeries B
Apreo Health
Aug 2025Participated
$130 MSeries B
Allay Therapeutics
Jun 2025Led
$58 MSeries D
Atsena Therapeutics
Apr 2025Participated
$150 MSeries C
FIRE1
Jan 2025Participated
$120 MOther Equity
Amber Therapeutics
Jun 2024Participated
$102 MSeries A
63
Items
...
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Insights

Time horizon

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Deal Distribution

Lightstone Ventures: 63 funding rounds are recorded in the selected participation categories.All available history.
Lightstone Ventures: 63 funding rounds are recorded in the selected participation categories. All available history
Round typeLed dealsParticipated deals
Seed10
Series A68
Series B317
Series C+312
Other Equity211

Monthly Deal Activity

Lightstone Ventures: 63 deals are recorded across 156 months.All available history.
Lightstone Ventures: 63 deals are recorded across 156 months. All available history
MonthDeals
Nov '131
Dec '130
Jan '140
Feb '140
Mar '140
Apr '140
May '140
Jun '140
Jul '140
Aug '141
Sep '141
Oct '140
Nov '140
Dec '140
Jan '150
Feb '150
Mar '151
Apr '150
May '150
Jun '150
Jul '151
Aug '150
Sep '150
Oct '150
Nov '150
Dec '150
Jan '160
Feb '161
Mar '161
Apr '161
May '160
Jun '161
Jul '160
Aug '160
Sep '160
Oct '161
Nov '160
Dec '161
Jan '170
Feb '170
Mar '170
Apr '170
May '170
Jun '171
Jul '170
Aug '170
Sep '170
Oct '172
Nov '170
Dec '170
Jan '181
Feb '180
Mar '181
Apr '180
May '181
Jun '181
Jul '180
Aug '180
Sep '180
Oct '180
Nov '180
Dec '180
Jan '190
Feb '191
Mar '190
Apr '190
May '192
Jun '190
Jul '190
Aug '190
Sep '191
Oct '191
Nov '190
Dec '191
Jan '200
Feb '201
Mar '200
Apr '201
May '200
Jun '200
Jul '200
Aug '200
Sep '202
Oct '201
Nov '202
Dec '203
Jan '211
Feb '211
Mar '210
Apr '212
May '210
Jun '210
Jul '210
Aug '211
Sep '210
Oct '210
Nov '210
Dec '210
Jan '220
Feb '220
Mar '220
Apr '220
May '220
Jun '220
Jul '220
Aug '220
Sep '221
Oct '220
Nov '220
Dec '221
Jan '232
Feb '231
Mar '232
Apr '231
May '230
Jun '231
Jul '230
Aug '230
Sep '231
Oct '230
Nov '230
Dec '230
Jan '240
Feb '241
Mar '240
Apr '241
May '240
Jun '241
Jul '240
Aug '240
Sep '240
Oct '240
Nov '240
Dec '240
Jan '251
Feb '250
Mar '250
Apr '251
May '250
Jun '251
Jul '250
Aug '253
Sep '252
Oct '250
Nov '250
Dec '251
Jan '260
Feb '260
Mar '260
Apr '260
May '261
Jun '260
Jul '261
Aug '260
Sep '260
Oct '260

Sector Breakdown

Lightstone Ventures: Health & Life Sciences is the largest displayed sector by deal count (58 deals).All available history.

A deal can appear in multiple sectors, so sector totals may overlap. Capital represents disclosed total round sizes, not fund cheque sizes.

Lightstone Ventures: Health & Life Sciences is the largest displayed sector by deal count (58 deals). All available history
SectorDeals
Health & Life Sciences58
Space & Frontier Tech9
Hardware & Robotics5
Consumer & Lifestyle3
Transportation & Logistics2
Networks, Cloud & Communication2
AI & Machine Learning2
Fintech1
Enterprise Software1
Manufacturing1
E-Commerce & Retail1
Food & Agriculture1

Deal Size Distribution

Lightstone Ventures: 63 rounds have a disclosed size in the displayed size bands.All available history.

Undisclosed round sizes are excluded. Capital represents total round sizes, not fund cheque sizes.

Lightstone Ventures: 63 rounds have a disclosed size in the displayed size bands. All available history
Round size band (USD)Deals
<$5M0
$5M-$10M2
$10M-$25M9
$25M-$50M21
$50M-$100M20
$100M-$250M11
$250M-$500M0
$500M-$1B0
$1B+0

Deals By Geography

Lightstone Ventures: United States has the largest recorded deal count among the displayed regions (46 deals).All available history.

Top 4 of 4 regions; European countries are grouped as Europe.

Lightstone Ventures: United States has the largest recorded deal count among the displayed regions (46 deals). All available history
RegionDeals
United States46
Europe13
Singapore2
India2
Lightstone Ventures: 20 co-investors are shown, with New Enterprise Associates sharing 14 recorded deals.All available history.

Co-Investors

Bubble size = shared deals

Click a bubble to open that fund in a new tab.

Shows up to 20 co-investors ranked by shared deals. Deals may be shared with multiple funds, so rows overlap. Capital is total round size, not fund cheque size.

Lightstone Ventures: 20 co-investors are shown, with New Enterprise Associates sharing 14 recorded deals. All available history
Co-investorShared deals
New Enterprise Associates14
Google Ventures10
Gilde Healthcare8
RA Capital Management7
Atlas Venture6
Medtronic6
Novo Holdings6
SR One6
SV Health Investors6
Osage University Partners5
ARCH Venture Partners4
Dementia Discovery Fund4
Gates Frontier4
Morgenthaler Ventures4
Pfizer Ventures4
Sante Ventures4
Temasek4
Vensana Capital4
Abingworth3
Alexandria Venture Investments3

Investment Strategy

Lightstone Ventures: Led accounts for 24% and participating for 76% of round participation.All available history.
Lightstone Ventures: Led accounts for 24% and participating for 76% of round participation. All available history
CategoryDeals (count)Share (%)
Led1524%
Participating4876%
Lightstone Ventures: Single-lead accounts for 27% and co-led for 73% of lead dynamics.All available history.
Lightstone Ventures: Single-lead accounts for 27% and co-led for 73% of lead dynamics. All available history
CategoryDeals (count)Share (%)
Single-lead427%
Co-led1173%

Team

Christina Isacson

Partner

Christopher M. Owens

Founder, President & CEO

Hank Plain

Partner

Jean George

General Partner

Ken Noonan

CEO, Lightstone Singapore Pte. Ltd.

Robin Bellas

Partener

Stacy Enxing Seng

Venture Partner

Stephanie White

Controller