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The Venture Codex

St. Louis Arch Angels

7750 Maryland Ave, St. Louis, Missouri, 63105, United States

Overview

We are a select group of accredited investors with diverse expertise and experience, seeking high potential start-up ventures drawn from the St. Louis startup ecosystem to fund and support, resulting in success of our funded companies and outsized returns for our members and corporate partners.

Total investments
14
Lead investments
2
Investments · 12mo
0
Active investors
5

Sector focus

  • Non Profit
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Investment portfolio

  • Maximum Fidelity Surgical Simulations

    Led · Seed · Jul 2024

    Maximum Fidelity (MaxFi) offers a patented, proprietary cadaver perfusion system that makes cadavers bleed, breathe and handle like live patients, enabling realistic operating room and trauma-care simulations. Its core customers include healthcare professionals, military medical personnel, and medical device manufacturers, with named customers such as Johnson & Johnson, Washington University in St. Louis, and Safeguard Medical. The company’s simulations are used for education, device testing, and research, positioning MaxFi as a specialized service provider in surgical training and medical device development. MaxFi plans to use the newly raised capital to build a leading-edge medical device development and surgical simulation center in St. Louis, equipped with labs, meeting spaces and lecture rooms. The funds will also support hiring full-time employees, development and launch of new technology, and expansion to new markets. Founded in 2014 in Columbia, Missouri, MaxFi emphasizes commercialization and scaling of its simulation services.

  • Covercress

    Participated · Equity · Apr 2020

    CoverCress develops a winter oilseed crop derived from field pennycress, branded CoverCress, intended to be planted after corn harvest and harvested before soybean planting. The crop is designed to enable three full-season crops in two seasons while delivering cover-crop environmental benefits such as soil carbon sequestration and reduced erosion. CoverCress's seed produces a low-carbon-intensity oil for renewable diesel, biodiesel and sustainable aviation fuel as well as a meal or whole-grain feed ingredient for livestock. Scientists have used plant breeding and advanced gene-editing tools to increase yield, accelerate maturity, and improve oil and meal quality. The company says the seed can provide a cash profit margin to farmers, and it markets the product as a regenerative, revenue-generating cover crop. CoverCress raised $8 million in partner funding to complete final crop development and scale up toward a planned commercial planting in fall 2022. CoverCress develops a new winter oilseed crop (CoverCress) derived from pennycress using plant breeding and genome‑editing tools. The crop is planted at corn harvest in fall and harvested immediately before soybean planting, offering farmers an additional cash crop while serving as a cover crop that builds soil health and holds nutrients over winter. Its grain contains oil and protein similar to canola and has a very low carbon intensity, attracting interest from bio/renewable diesel producers and firms seeking non‑GM protein meal. The company has grown to a team of over 20 and maintains partnerships with Illinois State University, the University of Minnesota, Western Illinois University, and participates in the USDA iprefer grant program. CoverCress plans a commercial launch in fall 2021 and aims to scale to millions of acres across the southern Midwest; the recent funding is intended to build the value chain to support that launch. Mike DeCamp joined as COO to focus on building the value chain for commercialization. CoverCress develops a gene-edited pennycress, branded Covercress, intended as a winter oilseed cash crop that also provides soil cover between corn harvest and soybean planting. The company uses conventional breeding, mutant-population screening with partner universities, and CRISPR to improve yield, maturity, oil content and composition. Its seed oil and press-cake meal are positioned as similar to canola, with higher-value oil and high protein for dairy and swine feed. CoverCress conducts research across three facilities in St. Louis’ 39 North district and has partnerships with the University of Minnesota and Illinois State. Management plans a first commercial crush and commercial launch in 2021 and is expanding its R&D team and field-farmer support headcount. The company says the business is more time- than capital-intensive and has secured runway of at least one year with this raise to complete its fifth field trial. Arvegenix is an ag biotech company engineering genetically improved field pennycress as an oil crop. The company completed a $2.4 million venture financing. The round included a long list of investors, with several agtech-focused backers among them. Named investors include agtech accelerator The Yield Lab, Cultivian Capital, and Monsanto Growth Ventures. Other participants were Michael Roth, the St. Louis County Port Authority, Prelude Ventures, Prolog Ventures, Missouri Technology Corporation, BioGenerator, and St. Louis Arch Angels. The raise was reported in an Agtech Funding Sheet covering Latin American startups, ag marketplaces, bio-inputs, sensors and more. Arvegenix is focused on improving pennycress, a wild mustard-family plant, as an oil-producing crop that can be grown in winter between corn and soybean seasons. The company aims to harvest oil-rich seeds and repurpose the leftover seed meal as livestock feed. Pennycress offers soil protection during winter, requires relatively low pesticide, fertilizer, and water inputs, and has attracted USDA support for biofuel research. Arvegenix plans to expand R&D to increase yields, conduct regulatory feeding studies on press-cake, and develop growing and crushing operations. The company launched in 2013 and is based in St. Louis. It has previously received investments from Helix Fund and Missouri Technology Corporation.

  • Canopy Biosciences

    Participated · Series A · May 2018

    Canopy Biosciences develops and commercializes research tools focused on gene editing and expression analysis. The company was founded in September 2016 and operates out of the BioGenerator Labs in St. Louis, Missouri. Its lead technology is licensed through Washington University in St. Louis and it already serves customers in Europe, India, Japan, and South Korea. Canopy has demonstrated a rapid path to revenue, launching four product lines and two services within the past year. The company plans to use new funding to develop additional research tools, commercialize cutting-edge products, and hire more employees. Canopy was founded by Edward Weinstein, David Smoller, and Crystal Winkeler.

  • Lean Media

    Participated · Seed · Feb 2018

    Lean Media is a Cheterfield, MO-based audience-first programmatic media company serving the agriculture industry and businesses targeting rural audiences. It provides agribusiness and rural community online advertisers with a platform that uses advanced data analytics and proprietary programmatic media buying methods to deliver cross-device ads with high frequency, precision and control. The company is led by co-founders Beth Handrigan (CEO) and Matt Jeter. Lean Media closed $500K in seed funding led by The Yield Lab, with participation from Prosper Startup Accelerator, The St. Louis Arch Angels, a private investor from the agriculture and media industries, and Missouri Technology Corporation. The company intends to use the funds to hire additional software engineering, data science, and ad tech staff and to develop software that will strengthen its market position. The raise is positioned to support product and team growth in its core rural and agribusiness advertising market.

  • Fluent

    Participated · Seed · May 2016

    Fluent operates a blockchain-based financial operating network that powers applications for global trade and the financial supply chain. The platform enables real-time B2B payments, supply chain finance, and a peer-to-peer working capital marketplace while aiming to reduce risk and streamline and automate settlement. The company spent nearly a year in stealth building the platform and working with enterprises to understand financial operations challenges. Fluent announced a pilot partnership with Commerce Bancshares, which has been participating in the Fluent Network pilot program since February 2016. The company plans to use new funding to grow its engineering team, bolster business development, and expand its sales force to serve banking partners and non-bank lenders. Fluent has raised a total of $2.5MM to date following a November 2015 pre-seed financing.

Team