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The Venture Codex

What If Ventures

6735 Salt Cedar Way Building 1, Frisco, Texas, 75034, United States

Overview

What If Ventures invests in stigmatized verticals within the healthcare market. For too long, stigma has artificially suppressed demand for care in indications such as mental health, fertility, and many others. Societal changes are creating markets where stigma once stood in the way of people getting the care they need. The firm was founded in 2019 by Stephen Hays, after his own personal struggles with mental health and addiction fueled his desire to see more funding for solutions in that space. Since then, the firm has broadened its aperture and has deployed nearly $80mm into more than 60 disruptive healthcare startups.

Total investments
20
Lead investments
0
Investments · 12mo
2
Active investors
2

Sector focus

  • Biopharma
  • Biotechnology
  • Health Care
  • Life Science
  • Mental Health
  • Personal Health
  • Pharmaceutical
  • Venture Capital
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Investment portfolio

  • Thea Energy

    Participated · Series B · May 2026

    Thea Energy builds pixel-inspired rectangular magnets and software to generate and fine-tune stellarator magnetic fields, using many smaller planar coils to shape plasma confinement. The company says its approach lets software control arrays of regular magnets to create complex stellarator fields, and it has built dozens of full-scale magnet iterations in its Jersey City lab. Thea originally spun out of the Princeton Plasma Physics Laboratory and has iterated its design to include a set of larger magnets alongside more than 300 smaller coils that fine-tune the plasma. With $130 million in total private funding after the new Series B, Thea is scaling magnet manufacturing and plans to begin construction of its Eos demonstration reactor next year. The company aims to complete Eos by 2030 and bring a commercial device, Helios, online in 2034.

  • Reliable Robotics Corporation

    Participated · Equity · Apr 2026

    Reliable Robotics develops the Reliable Autonomy System (RAS), an FAA-certifiable autonomy stack designed to enable fully automated aircraft operations and prevent the leading causes of aviation accidents. The company says RAS is built to integrate with certified aircraft and existing aviation infrastructure without changes to the National Airspace System. Reliable has secured commitments for over 200 systems from commercial and military customers, been selected for the Department of Transportation’s eIPP advanced aviation pilot program, and holds a contract to provide automated air cargo operations for the U.S. Air Force. The business has been advancing FAA certification—having had its certification plans and means of compliance accepted—and is delivering required compliance materials under the FAA-agreed plan. Since its last financing the company has nearly tripled its workforce and plans to use the new $160M to expand production facilities, grow headcount, and accelerate deployment toward autonomous cargo operations in 2026. The company is headquartered in Mountain View, California and maintains a distributed global workforce.

  • Saildrone

    Participated · Equity · May 2025

    Saildrone develops unmanned surface vehicles (USVs) powered primarily by wind and solar that carry sophisticated sensors and proprietary AI to monitor the maritime environment above and below the surface. Its Voyagers deliver long-duration operations measured in months and support use cases including border protection, critical infrastructure security, and hydrographic survey. The company has sailed more than 2,000,000 nautical miles and spent over 50,000 days at sea across the High North to the Southern Ocean. Saildrone is expanding its operational footprint in Europe and will establish a European headquarters and operational hub in Copenhagen, Denmark. As part of that expansion, it plans to roll out maritime intelligence services to multiple NATO countries and provide 24/7, year-round coverage for critical infrastructure in the Baltic and North Sea. The company recently closed a $60 million financing to accelerate these European deployments and defense partnerships. Saildrone develops and operates autonomous science vessels (USVs) used for ocean mapping, data collection, and marine intelligence. Its fleet has collectively traveled half a million miles and is deployed on missions that would be too dangerous or tedious for human crews, including a NOAA project that sent a vessel into a hurricane. The company’s newest craft, the Surveyor, can spend a year at sea and map the ocean floor beyond two miles of depth. Saildrone positions its systematic data collection to support scientific research, ship routing, and sustainable aquaculture as the ocean economy grows. To capture more of the emerging 'ocean domain intelligence' market it plans to scale production, hire "data insight teams," and expand go-to-market functions. The recent funding is intended to accelerate that scaling and further development of its fleet. Saildrone develops and operates a fleet of unmanned surface vehicles (ocean drones) to collect high-resolution ocean observations. The company sells ocean infrastructure and data used for weather analysis, fisheries management, and in‑situ ocean science. It has partnered with US agencies including NOAA and NASA and announced a multi‑year collaboration with Australia’s CSIRO, opening operations in the Southern Ocean from Hobart, Tasmania. Saildrone recently opened a 200,000 square foot advanced manufacturing facility in Alameda, California to support scale‑up. The company plans to use new capital to scale its global fleet and monitor the state of the planet in real time. Since its commercial debut in 2016 the company has raised almost $90m in total. Saildrone operates wind- and solar-powered unmanned surface vehicles (USVs) that collect ocean and atmospheric measurement data. The company’s fleet has sailed over 60,000 nautical miles on missions in the Atlantic, Pacific, Gulf of Mexico and Bering Sea. Leadership is led by founder and CEO Richard Jenkins with Sebastien de Halleux as COO. Saildrone plans to use new capital to expand its fleet, enhance data processing capacity and scale commercial operations. The company closed a $14M Series A to support those plans. Prior to the round it received a mission-related investment from The Schmidt Family Foundation.

  • Raven Space Systems

    Participated · Seed · Nov 2024

    Raven Space Systems has developed a patented Microwave Assisted Deposition (MAD) 3D printing process that cures thermoset composites during printing, enabling the first scalable production of off-the-shelf thermoset composite parts. The cofounders, Blake Herren and Ryan Cowdrey, began the work as graduate students at the University of Oklahoma and the company is based in Kansas City, Missouri. Raven has received about $1M in SBIR grants and, since 2020, roughly $4.5M in non-dilutive contracts and awards from the Air Force, NASA, the National Science Foundation and others. The startup recently closed a $2M pre-seed round to fund its first full-scale manufacturing lines — production-scale 3D printers, mixing systems and machining. Raven plans to move from its 3,000-square-foot facility into a larger, aerospace-certified factory by Q2 next year and to begin manufacturing customer components, starting with smaller parts and scaling up. Initial go-to-market targets are thermal protection components for solid rocket motors and hypersonic vessels, and the company is also engaged with autonomous systems providers, satellite manufacturers and space propulsion firms; it announced a partnership with SpaceWorks to develop 3D-printed reentry vehicle aeroshells.

  • Grayce

    Participated · Series A · Jun 2024

    Grayce combines a high-touch social work care model with a digital platform to help family caregivers navigate medical, eldercare, childcare, and other complex care needs. Each member receives dedicated support from Masters-level social workers who plan, coordinate, advocate, and connect members to resources, peer communities, educational content, and a marketplace. The platform is personalized and culturally tailored, available globally in over 250 languages. Grayce reports employer customers have seen turnover fall by 38%, 50% of employees avoided taking leave or reducing hours, nearly 80% of members feel more valued, and customers have reported a sixfold return on investment. Founded in 2019 and headquartered in San Francisco, the company is focused on expanding multi-generational care offerings and building trusted employer and payer solutions. Future plans include scaling the employer solution and member experience, entering the payer market, investing in data-driven personalization, and strengthening community and content offerings.

Team