Participated · Series A · Dec 2025

Clarity Pediatrics operates a tech-enabled virtual clinic that delivers American Academy of Pediatrics–aligned specialty care for chronic pediatric conditions such as ADHD and anxiety. More than 1,600 pediatricians in California and Texas already refer both commercial and Medicaid patients to the service, which integrates medical oversight, behavioral therapy, and parent coaching, all covered by insurance. Outcomes to date are encouraging: 89% of participating parents report a ‘large’ impact on their lives and 75% see improvement in child behaviors after eight weeks. The company plans to launch obesity care in early 2026, broadening its multi-specialty offering to address one of the fastest-growing pediatric health issues. Funding will also support continued development of its virtual platform and geographic expansion across the United States. Clarity’s model emphasizes family-centered group care delivered by pediatricians and specialists working at the top of their licenses. The company is headquartered in San Francisco and is backed by several prominent venture investors.

Participated · Equity · Oct 2025

knownwell delivers evidence-based obesity treatment that combines metabolic health services, primary care, nutrition counseling, and behavioral health, all covered by insurance and offered virtually nationwide and at select physical clinics. Its physician-designed care model emphasizes respectful, longitudinal engagement, producing a >90 net promoter score, 91% one-year patient retention, and 93% sustained weight loss after one year. Over the last 18 months the company has expanded from Massachusetts into Georgia, Illinois, and Texas while activating virtual care in all 50 states. This approach targets a market in which obesity drives more than $260 billion in annual U.S. healthcare costs. Management views payer and health-system alignment as critical and positions knownwell as a scalable, value-based partner for those stakeholders. The company has now raised more than $50 million in total funding, including the latest $25 million round, to fuel further geographic growth and platform development.

Participated · Seed · Sep 2025

florrent is an energy technology company that produces supercapacitors using a proprietary bio-derived activated carbon called Contoured Carbon. Their material diverts domestic biomass waste from landfills and sequesters carbon while enabling high-power, lower-cost, smaller-footprint energy storage. florrent’s supercapacitors are made in the U.S. and designed to integrate front-of-meter and behind-the-meter, offering grid-forming capabilities, fast frequency response, and improved power quality. The company emphasizes social and environmental impact through sourcing strategies that create economic participation for historically underserved communities. florrent plans to scale production of Contoured Carbon, expand product development, and commercialize broadly while building a pilot manufacturing facility in Northampton, MA, scheduled to begin operations in 2026. The business frames its product as a solution to a reported $150B/year power quality problem during the ongoing grid transformation.

Participated · Series A · Aug 2025

Reframe Systems develops regional, deployable microfactories that use proprietary software, vision-guided robots, and physical AI to automate framing, sheathing, and insulation and enable mass-customized, site-specific homes. Its microfactories can be launched in 100 days and manufacture up to five single-family homes per week, delivering homes 2.5× faster while reducing costs by 35%. Homes produced are designed to meet local codes and resilience standards — all-electric, solar-ready, and built with fire-resilient materials and features. The company was founded by former Amazon Robotics leaders Vikas Enti, Felipe Polido, and Aaron Small and is accelerating projects in the Boston area (Somerville, Devens, Woburn) and pilot work in Altadena, CA, with plans for a Southern California microfactory. Reframe aims to scale its model widely with a stated mission to build one million homes by 2045. The Series A capital will support scaling its microfactory network and deployment to address the U.S. housing shortage and construction labor shortfall.

Participated · Equity · Feb 2025

Bitwise Asset Management is a crypto-specialist asset manager that offers a broad suite of 32 investment solutions across beta, alpha, and onchain strategies. Its product set includes yield and alpha strategies, multi-strategy solutions, separately managed accounts, onchain staking, index funds, and bitcoin ETPs. The firm ended 2024 with more than $12 billion in client assets after more than 10x growth during the year. Proceeds from the $70 million equity raise will bolster the firm's balance sheet and accelerate buildout of investment capabilities and investor solutions. Bitwise has offices in San Francisco, New York, and London and employs more than 100 technology and investment professionals, with plans to grow headcount to over 130 this year. More than 5,000 wealth teams, RIAs, family offices, institutional clients in the U.S. and Europe, and over 15 banks, broker-dealers, and platforms use Bitwise products. Bitwise Asset Management is a cryptoasset manager that runs a large crypto index fund (OTCQX: BITW) and a suite of products including the Bitwise 10 Crypto Index Fund, Bitwise Bitcoin Fund, Bitwise Ethereum Fund, and targeted products for DeFi and crypto equities. The firm recently launched the Bitwise DeFi Crypto Index Fund and the Bitwise Crypto Industry Innovators ETF (NYSE: BITQ), which tracks the Bitwise Crypto Innovators 30 Index of pure-play crypto equities. Bitwise focuses on partnering with financial advisors and investment professionals, providing education and research alongside its product lineup. The company manages over $1.2 billion in assets across its investment solutions and is currently profitable. Bitwise plans to use new capital to strengthen its balance sheet and accelerate a national buildout of its organization, team, and product suite. The firm is led by CEO Hunter Horsley and is based in San Francisco, CA. Bitwise Asset Management, founded in 2017 by Hunter Horsley and Hong Kim, is a San Francisco-based cryptocurrency investment startup. The company develops funds, indexes, insight, and other services for individuals, wealth managers, family offices, investment managers, and institutions. It is launching the Bitwise HOLD 10 Private Index Fund, a cryptocurrency index fund that holds the top-10 most valuable crypto-assets selected and weighted by market capitalization. The fund rebalances monthly and is designed to capitalize on hard forks and airdrops. Bitwise raised $4M in seed funding from a group of investors to support its product and growth plans.