Participated · Seed · Aug 2022

Remedium Bio is advancing a proprietary Prometheus™ platform designed to enable controlled, long-lasting expression of therapeutic proteins by harnessing adipocytes as a durable site for production. The platform aims to provide multi-year benefit with adjustable dosing following minimally invasive subcutaneous administration and to replace many subcutaneously administered protein therapies with single-injection, adjustable gene therapies. Its pipeline includes programs targeting endocrinology, immunology, neurology, and musculoskeletal diseases. The company recently completed an initial closing of a $10 million Series A led by LifeSpan Vision Ventures, with participation from Eli Lilly and Company and HKX Capital. Remedium is using the financing to advance lead programs, expand the platform, and prepare for first-in-human clinical studies. The announcement was issued from Norwalk, Connecticut.

Participated · Seed · Jun 2022

Impossible Mining builds responsible seabed mining and refining technology with a focus on deep‑sea robotics and Bio‑Extraction. Based in San Jose and a graduate of Y Combinator's W22 batch, the company is developing a four‑mile‑deep robotic collection system to selectively recover battery metals from the seafloor. It is also developing Bio‑Extraction refining technology intended to process recovered materials in an environmentally responsible way. The team says its approach aims to preserve the seafloor environment compared with dredge‑based methods. Impossible Mining closed an additional $10.1 million in seed funding to fund development and testing of its deep‑sea robotics and to continue advancing its extraction technology. Leadership has emphasized the strategic importance of securing independent access to critical battery metals amid rising lithium‑ion battery demand.

Participated · Series A · Jun 2022

Anfin offers a mobile-first stock trading app that provides fractional trading (as little as 10,000 VND), proprietary stock profiling and risk-assessment tools, and social investment features including live audio rooms and a ranked newsfeed. The app currently lists about 300 stocks and nine ETFs and emphasizes educational content for its primarily Gen Z and millennial user base (90% are 18–35). Since launching in October 2021, Anfin has been downloaded more than one million times and has about 100,000 funded accounts; deposits have reached up to $5 million and total transaction value up to $10 million, with average transaction values around $20. Anfin monetizes through trading commissions and a subscription product called Anfin VIP, and it explicitly does not use payment for order flow or sell user data; it routes orders through Vietnam’s regulated exchanges via brokerage partners. The company plans to add more financial asset classes and expand its social-investing features, including influencer-driven incentives and further community tools. Leadership frames the product as a way to lower the cost of investing in Vietnam by offering fractional shares and instant settlement options via spread or liquidity provision.

Participated · Equity · Oct 2021

Bucha Bio is a Houston, TX-based biomaterials science company developing biobased materials for multiple industries. It is developing two materials, SHORAI—an alternative to animal leather, plastic leather, or other synthetic materials—and HIKARI, a translucent material with processing capabilities that will be formally introduced in November. The company raised $1.1M in Seed funding to accelerate its move to market. Backers include New Climate Ventures, Lifely VC, Beni VC, Prithvi VC, Asymmetry VC, Alwyn Capital, and Chris Zarou. Bucha Bio plans to use the funds to secure co-manufacturers to scale material production and to support construction of a new Houston headquarters. It also plans to enable new form factors, including biofibers, biopackaging, and hard biocomposites, targeting industries such as fashion, automotive, home goods, electronics, and construction. Bucha Bio develops novel biomaterials from fermented bacterial nanocellulose and plants. The company designs next-generation materials with applications in textiles, packaging and hard construction materials. An expansive library of plant-based formulations combined with a proprietary consortium of bacteria underpins its material innovations. Bucha offers a signature luxury biotextile, MIRAI™, inspired by the Japanese word 'future' and the Italian phrase 'look with emphasis', which is available for reservation. Founded in 2019 and a graduate of SOSV's IndieBio program, the New York-based company plans to scale production of MIRAI™. It raised $550K in funding to support that scale-up.

Participated · Series B · Jul 2021

Mighty Buildings develops 3D-printed, prefab kits and factory-built components for residential construction, using a proprietary material made of 60% recycled glass. The company manufactures parts off-site using ultraviolet curing and microfactories to enable rapid, repeatable production and automotive-grade quality control. Its printed material is described as stronger and lighter than concrete, rated for winds up to 150 mph, and compliant with California building codes including Title 24 energy requirements. Mighty shifted from selling homes directly to selling whole communities and kits to developers, aiming for larger-scale projects. The company reported roughly $5 million in revenue in 2022 and says it has a pipeline of projects in the U.S., Caribbean and Middle East potentially worth “hundreds of millions.” Mighty Buildings, based in Oakland, CA, develops construction technologies that combine 3D printing, robotics, and advanced composite materials to create panelized building systems and modular homes. The company produces a range of projects from pre-designed ADUs to single-family developments using its Mighty Kit System. Mighty Buildings is building a network of micro-factories intended to produce 200–300 homes per year in locations with housing gaps. Leadership includes CEO Slava Solonitsyn and Chief Sustainability Officer Sam Ruben. The company is pursuing a carbon neutrality roadmap that emphasizes high-throughput sustainable micro-factories, strategic supply-chain partnerships, blue-skies technology research, and new composite materials made from recycled or bio-based feedstock. As of the article, Mighty Buildings had raised a total of $100M to date. Mighty Buildings is an Oakland-based construction technology company that 3D-prints prefabricated homes and accessory dwelling units using robotics, automation and a proprietary thermoset composite called Light Stone Material (LSM). The company says its process can 3D print a 350-square-foot studio in 24 hours, operate two times faster with 95% less labor hours and produce 10-times less waste than conventional construction, and automate up to 80% of the construction process through robotic post-processing and automated insulation pouring. It manufactures panelized 3D-printed exterior shells and prefabricates certain modules (like bathrooms) in a 79,000-square-foot Oakland production facility and is currently building only in California. Mighty Houses, its single-family product line, ranges from 864 to 1,440 square feet with estimated prices of $304,000 to $420,500, and the company has produced and installed a number of ADUs and secured developer contracts. The company plans to scale production capacity and automation with the new capital, market a Mighty Kit System and a new fiber-reinforced material for multi-story projects, and develop a B2B platform to offer production-as-a-service to builders and developers. Mighty Buildings launched out of stealth last August, is a four-year-old startup and has been included on Y Combinator’s Top Companies list; the company declined to reveal its current valuation. Mighty Buildings provides a production-as-a-service platform that combines 3D printing and prefab techniques to automate up to 80% of the building process. Its factory-driven approach can 3D-print components, panels, and full-size volumetric modules, and a 350-square-foot studio unit can be printed in under 24 hours. The company reports building with 95% fewer labor hours, at double the speed of conventional construction, and producing 10x less waste; its homes cost up to 45% less than comparable traditional homes, with automated production costs 20–30% lower than traditional prefab. Mighty Buildings is certified under California’s Factory Built Housing program and was first to achieve UL 3401 certification for 3D-printed building structures and assemblies. It has installed its first two accessory dwelling units in San Ramon and San Diego and says it is ready to scale production. The company graduated from Y Combinator in winter 2018 and is launching out of stealth from San Francisco.