The Venture Codex Logo

The Venture Codex

OpenAI

3180 18th Street, San Francisco, CA, 94110, United States

Overview

OpenAI is an AI research and deployment company that conducts research and implements machine learning. The research organization is dedicated to advancing artificial intelligence safely and beneficially. OpenAI aims to advance artificial general intelligence (AGI) that is safe, beneficial, and aligned with human values. The company focuses on creating AI systems that are capable of performing a wide range of tasks and learning autonomously from diverse data.

Total investments
48
Lead investments
19
Investments · 12mo
14
Active investors
9

Sector focus

  • Agentic AI
  • AI Infrastructure
  • Artificial Intelligence (AI)
  • Foundational AI
  • Generative AI
  • Information Services
  • Information Technology
  • Machine Learning
Visit website

Investment portfolio

  • Physical Intelligence

    Participated · Equity · Aug 2026

    Physical Intelligence develops pi, a vision-language-action foundation model intended to control diverse robot bodies and perform dexterous manipulation tasks. The company open-sourced pi-0's weights and has showcased demos such as folding laundry, bagging groceries, and making coffee. Founded in 2024 in San Francisco, the team is deliberately small (about 50–100 people) and includes academics and former industry researchers like Karol Hausman, Sergey Levine, and Chelsea Finn. It has raised roughly $2.1 billion to date but reports no revenue and no fixed commercialization timeline, prioritizing research. The company's thesis is that a single general robot brain can generalize across hardware, and its fundraising has attracted major investors including Jeff Bezos, OpenAI, CapitalG, Founders Fund, and Lightspeed.

  • Chai Discovery

    Participated · Series C · Jul 2026

    Chai Discovery develops AI models that reason about biological structure and function to generate new molecular designs from scratch and put those models into a software platform used by pharma teams. The company reports partnerships and deployments with major pharmaceutical firms, including Eli Lilly and Pfizer. Its model lineup includes Chai-2, released in 2025 as the first zero-shot generative platform for fully de novo antibody design to achieve double-digit experimental success rates, and Chai-3, which materially improves target success rates and binding affinity versus its predecessor. Founded in 2024 and based in San Francisco, Chai aims to bring engineering precision, speed and scale to pre-clinical discovery. The company recently raised $400M in a Series C at a $3.8B valuation to accelerate R&D, deployment and partnerships.

  • Poetic

    Participated · Series A · Jun 2026

    Poetic is building AI-driven automation tools aimed at streamlining complex, judgment-heavy business workflows. The company operated in stealth prior to announcing the $50 million investment and has shared limited public information about its leadership, technology, or development timeline. Its stated focus is automating tasks that traditional software struggles to handle, targeting enterprise customers. The $50 million backing from OpenAI provides a strategic relationship with a leading model provider, though no financial metrics or valuation were reported. Poetic is entering a crowded market of automation and agent-building startups, and the report does not include user, revenue, or growth metrics. The company’s future plans beyond using the funding to scale its product and go-to-market were not detailed in the coverage.

  • Biossil

    Participated · Equity · Apr 2026

    Biossil is developing an AI-driven drug development platform aimed at finding and reviving pharmaceutical compounds that were previously abandoned in clinical development. The company surfaced from stealth concurrent with its financing announcement. Its stated focus is to use artificial intelligence to reassess and advance failed or shelved drug candidates. Biossil has secured approximately $70 million in equity backing to fund platform development and related activities. Investors named in the financing include OpenAI, Founders Fund, and Staircase Ventures. The article did not disclose operational metrics, revenue, a valuation, or a detailed product roadmap.

  • Anchr

    Participated · Seed · Mar 2026

    Anchr is a New York City–based company developing an AI-driven “Enterprise Resource Automation” platform for food distributors. The software overlays existing ERP systems and embeds AI teammates that handle order intake, purchasing, inventory planning, and financial reconciliation while providing real-time margin intelligence for businesses operating on thin margins. Within 12 weeks of commercial launch, the company achieved seven-figure revenue and now serves customers ranging from regional seafood distributors to a publicly traded enterprise with $5 billion in revenue. With its fresh capital, Anchr plans to deepen automation across every operational layer of food distribution and to extend its platform into broader physical supply-chain markets. The company is led by co-founders and co-CEOs Tzar Taraporvala and Smayan Mehra. Its immediate focus is on scaling the engineering team and accelerating product development to maintain rapid growth and expand market reach.

Team

  • Sam Altman

    Co-Founder and CEO

  • Greg Brockman

    President, Chairman, & Co-Founder

    LinkedIn
  • Arvind KC

    Chief People Officer

    LinkedIn
  • Jason K.

    CSO

    LinkedIn