Up2 Opportunity Fund
13842 Lake Avenue, Lakewood, OH, 44107, United States
Overview
Up2 Opportunity Fund is a venture capital fund with promising tech startups from earlier funds.
- Total investments
- 5
- Lead investments
- 0
- Investments · 12mo
- 1
- Active investors
- 0
Sector focus
- Finance
- Funding Platform
- Venture Capital
Investment portfolio
- WellTheory
Participated · Series A · Oct 2025
WellTheory offers a research-backed, virtual care program that addresses the root causes of autoimmune conditions through diet, lifestyle, and high-touch support from registered dietitians and certified health coaches. Its AI-powered platform, featuring proprietary tools Care Hub and Care Scribe, personalizes care plans and supports scalable delivery. In just 18 months on the market, the company has secured partnerships with Fortune 100 and 500 employers, high-growth companies such as Maven Clinic, Fortune Brands Innovations, and Dayforce, as well as payors like Sentara Health Plans and a top national payor. Independent claims analyses show the service reduces ER visits, imaging, hospitalizations, and biologics use, saving partners thousands of dollars per patient annually. Over the last year, WellTheory recorded 10× year-over-year member growth and 5× revenue growth, highlighting strong demand and business traction. With the latest financing, the company has raised $26.2 million in total and plans to deepen employer and payor partnerships, expand programs targeting high-cost autoimmune conditions, and further invest in its AI personalization capabilities.
- Medeloop
Participated · Series A · Nov 2024
Medeloop is an AI-driven medical research platform based in Menlo Park, California. Led by CEO Rene Caissie, it automates the entire research cycle—from grant discovery to data analysis—by transforming medical data into a graph database to deliver deep insights and fast results. Its suite includes a grant platform for identifying and applying for funding, a dual-component studies platform (mobile app for participants and web app for researchers), a no-code analytics platform, and a manuscript publication platform. These integrated tools are designed to let researchers manage every aspect of a study from inception to publication. Medeloop partners with healthcare institutions worldwide. The company intends to use the new funds to expand operations and accelerate development efforts. Medeloop offers an AI-driven platform that integrates, harmonizes, and analyzes health data using advanced AI tools to support clinical research. The product streamlines researcher discovery and simplifies grant applications, data collection and harmonization, biomarker and trend identification, and manuscript submissions. Medeloop says these insights have the potential to expedite the clinical research process. The company plans to use the funds to launch an end-to-end solution for early-stage clinical research. Leadership includes CEO Dr. Rene Caissie, CTO Raghav Samavedem, CSO Dr. Josh Walonoski, and COO Andy Yakulis. Medeloop is based in Palo Alto, CA.
- OnStation
Participated · Series A · Jun 2024
OnStation is a Cleveland, OH-based provider of a collaborative digital stationing platform tailored to the heavy highway industry. Its mobile app centralizes communication and delivers location-based project records from bid to close, with instant jobsite stationing, milepost, and LRS capabilities. Users can overlay design layers on project maps and communicate via a custom chat platform that organizes and records project events at their locations. The platform is designed to boost productivity, enhance worker safety, and improve project quality across civil engineering and roadway projects. OnStation is available on the Apple App Store and Google Play and is supported on desktop systems. The company intends to use the newly raised funds to accelerate growth, expand its customer base, and enhance its platform. OnStation is a mobile application that enables better communication, location-based documentation, and streamlined issue tracking for road construction projects. The app serves as a complementary plugin to larger road construction tech solutions and provides access to project design files and contract documents. It is currently in use in 23 states and reports its customer base grew seven-fold over the past seven months. OnStation plans to use new funding to scale nationally, hire sales professionals and additional developers, and automate the project onboarding process. Leadership credits JumpStart Cleveland for four years of mentorship and support, and the product was built by founder and CTO Jake Bailosky based on his experience at the Ohio Department of Transportation. The company intends to add functionality and grow headcount to meet anticipated demand if federal infrastructure funding increases roadway projects.
- AIKON
Participated · Series A · Sep 2022
Aikon provides Web3 onboarding solutions built on the Open Rights Exchange (ORE) Network and powered by the ORE Token, with a focus on secure multi-chain authentication and wallet creation through its ORE ID product. Led by CEO Marc Blinder, ORE ID supports multiple blockchains including Ethereum, Polygon, Algorand, Telos and WAX and is being extended to support Avalanche. ORE ID is integrated into businesses and dApps such as AllianceBlock, RFox, NFT Battle Miners and EarnFi and is actively used in 12 countries. The company is targeting 400,000 ORE ID users by the end of 2022. Aikon intends to use its recent funding to grow its team of blockchain experts to support rising demand, and the company added board members Mark Yusko and W. Scott Stornetta in conjunction with the round.
Team
No current team members are available.