Difference Partners
589 5th Ave, New York, NY, 10012, United States
Overview
Difference Partners is a $30M early-stage fund investing in companies that improve the lives of those who learn and think differently (autism, ADHD, dyslexia and related neurodiversity).
- Total investments
- 7
- Lead investments
- 0
- Investments · 12mo
- 2
- Active investors
- 1
Investment portfolio
- Valence AI
Participated · Seed · Jun 2026
Valence AI develops Pulse Emotion models and a patented audio signal processing pipeline that analyze live calls to classify emotional state from speech in real time, converting tone, pacing, and vocal cues into structured data. The company publishes its own foundation models trained on proprietary, demographically and neurotype-diverse speech datasets and reports 92% accuracy on internal benchmarks. Products include emotion-aware IVR, an Agent Assist copilot for live call coaching, emotionally intelligent AI voice agents, and post-call quality assurance; integrations include ElevenLabs and Cartesia. In production deployments Valence reports handle time reductions of 30% and improvements in customer satisfaction scores, close rates, and time to close, and it serves customers such as Harte Hanks, CustomerHD, and BPO Centers. Valence holds two U.S. patents issued in June 2026 covering its core signal processing pipeline and an extension for live haptic feedback, and its offerings are SOC 2 Type 2 and HIPAA compliant. The company plans to expand language coverage and deepen platform integrations as part of its near-term roadmap.
- Hipp Health
Participated · Seed · Oct 2025
Founded in 2024 in San Francisco by David Connors and Faaez Ul Haq, Hipp Health provides behavioral health providers with an AI-powered platform designed to reduce paperwork and improve compliance. The software automates data collection, clinical notes, scheduling, and session compliance while embedding analytics directly into clinical and operational workflows. It also expedites billing through automated claims validation and follow-up solutions, addressing complex Medicaid requirements. The company targets the hundreds of thousands of behavioral health practitioners in the United States who struggle with administrative overhead. Hipp Health plans to use newly raised capital to accelerate product development, expand its San Francisco team, and further refine its AI capabilities. Although still early-stage, the company positions itself as an essential infrastructure layer for behavioral health operations. No revenue or user figures have been publicly disclosed.
- Marker Learning
Participated · Series A · Feb 2023
Marker Learning offers remote learning and attention-disability evaluations and ongoing support, leveraging proprietary technology and a network of psychologists and educators. The company delivers comprehensive diagnostic reports within one month that can be submitted to schools or employers and used to secure test accommodations. Marker partners with school districts to act as an extension of special education teams and already reaches 1 million students through those partnerships. It aims to provide services at a fraction of the cost of traditional private evaluations—which can cost up to $14,000 and have waitlists beyond 24 months—to improve equity for students of color and low-income households. With Series A funding, Marker plans to expand into new geographies and broaden its platform to include tutoring, coaching, and other learning support services for individuals and schools. Co-founders Stefan Bauer and Emily Yudofsky, both diagnosed with dyslexia, lead the company. The company announced a $15 million Series A led by Andreessen Horowitz. Marker Learning operates a telepsychology platform that enables psychologists to virtually administer evidence-based learning disability assessments and deliver personalized action plans. The company partners with leading psychologists and learning-disability specialists and leverages proprietary technology to streamline the assessment process, reduce cost, and decrease turnaround time versus in-person services. Evaluations for dyslexia and other learning disabilities often cost over $10,000 and many cases go undiagnosed; Marker aims to make gold-standard assessments more accessible to schools and families. The platform was developed to address long waitlists and access issues that were exacerbated by the COVID-19 pandemic. Marker plans to use new funding to expand its team and accelerate geographic expansion across the United States. Co-founders Stefan Bauer and Emily Yudofsky started the company after their own diagnoses and bring experience from McKinsey, Google, and telemedicine entrepreneurship.
- AnswerNow
Participated · Series A · Feb 2023
AnswersNow operates a custom-built virtual platform for digital Applied Behavior Analysis (ABA) that pairs families with a dedicated clinician for therapy sessions designed to mirror an in-person controlled environment. The platform includes special screen features to eliminate distractions and integrated activities focused on memory and recognition to engage clients. AnswersNow plans to use new funding to expand its ABA therapy services into more U.S. states, grow its team of PhD- and Master’s-level clinicians, and improve the user experience of its interactive virtual platform. The company employed a clinical team that facilitated more than 10,000 hours of therapy in 2022. AnswersNow currently employs a nationwide network of clinicians and partners with major health insurers, including Medicaid, United Health Care, Aetna, Cigna, Anthem and Blue Cross Blue Shield. The company is led by CEO Jeff Beck and was founded in 2017 in Richmond, VA.
- AnswersNow
Participated · Series A · Feb 2023
AnswersNow is a Richmond-based health-tech company that offers personalized, virtual applied behavioral analysis (ABA) therapy to families of children with autism. Its AI-driven platform creates individualized learning modules that adapt to each child’s interests, aiming to raise the immediacy, accessibility, and quality of care. The service is already available as in-network coverage with multiple commercial insurers and Medicaid across several states. Led by CEO Jeff Beck, the company positions itself as an affordable, scalable alternative to traditional in-person ABA therapy. With the new capital, AnswersNow plans to enhance its technology stack, expand its clinical and operational team, and deepen its AI capabilities to drive further personalization and efficiency. Prior to the latest round, the startup had attracted backing from Left Lane Capital and Owl Ventures, although earlier funding amounts were not disclosed.
Team
Jesse Morris
Founder & General Partner
LinkedIn