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The Venture Codex

Route 66 Ventures

118 King Street, 2nd Floor, Alexandria, VA, 22314, United States

Overview

Route 66 Ventures is a private investment firm focused on helping entrepreneurs shape the financial services landscape of tomorrow by providing Venture Capital and Credit solutions to emerging financial technology and services companies. Route 66’s Venture Capital team invests globally in early and growth stage disruptors, incumbents and service providers throughout various sectors in the financial services ecosystem. Route 66’s Credit team seeks to fund alternative lending platforms and business models with balance sheet needs by purchasing whole loans or providing secured debt facilities.

Total investments
58
Lead investments
19
Investments · 12mo
1
Active investors
6

Sector focus

  • Consumer Lending
  • Credit
  • Financial Services
  • FinTech
  • Insurance
  • Venture Capital
  • Wellness
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Investment portfolio

  • Auxira Health

    Led · Seed · Dec 2025

    Auxira Health operates a virtual cardiology platform that pairs advanced practice providers, medical assistants and registered nurses with cardiology practices as fully integrated remote “pods.” These virtual teams handle clinical and administrative tasks, allowing on-site cardiologists to see more patients and reduce workload. The company partners with cardiology groups and health systems nationwide, positioning its service as a scalable way to address specialist shortages and administrative burden. Led by CEO Inna Plumb, Auxira Health is building out technology and operational infrastructure to support seamless integration with partner clinics. The firm plans to hire additional clinicians and support staff to meet rising demand. By mid-2026, management expects the platform to support more than 100 cardiologists. The recent seed funding provides the financial runway to accelerate these growth initiatives and deepen product capabilities.

  • EarthOptics

    Participated · Equity · Nov 2024

    EarthOptics leverages advances in soil-sensing technologies, genomics, and data science to deliver predictive insights into chemical, physical, and biological soil properties. It combines lab-based analysis with field-based sensors to give farmers and ranchers actionable recommendations to optimize spending and unlock sustainable farming opportunities. The company completed a strategic merger with Pattern Ag, combining EarthOptics’ proprietary field-based sensing technologies with Pattern Ag’s lab-based analysis to offer comprehensive soil data. Led by CEO Lars Dyrud, EarthOptics operates offices in Raleigh, North Carolina; Emeryville, California; Arlington and Blacksburg, Virginia; Minneapolis, Minnesota; and Fayetteville, Arkansas, and maintains two laboratories in Emeryville and Memphis, Tennessee. The company intends to use new funding to accelerate technological innovation, broaden its geographic reach, and consolidate its position as an authoritative source for soil insights. EarthOptics develops next-generation soil-sensing technologies that combine ground-based sensors, satellites, physical soil samples, machine learning models, and agronomic expertise to deliver detailed soil measurements. The company's platform provides insights to help farmers optimize fertilizer applications, inform tillage decisions, and quantify carbon sequestration. EarthOptics plans to use its latest funding to expand access to its tools and deliver hyper-accurate soil insights. Founded in 2018 and based in Arlington, VA, the company serves growers and ranchers seeking data-driven land-management decisions. The company is led by CEO Lars Dyrud. The article reports a recent financing that will support its growth and product expansion efforts. EarthOptics has developed an imaging suite that uses ground-penetrating radar and electromagnetic induction to produce deep maps of soil physical and chemical composition. Its commercial products, GroundOwl and C-Mapper (C for carbon), reconcile no-contact sensor data with traditional lab samples via machine learning trained on tens of thousands of ground-truth measurements. The hardware can be mounted on ordinary tractors or trucks and pulls readings every few feet, reducing physical sampling from hundreds of samples to dozens. The company’s outputs can be used to create meter-scale treatment maps or to feed variable-depth robotic field machinery such as smart tillers. Management positions the product as a cheaper, faster, and more precise alternative to traditional soil sampling and as foundational data for automated and robotic farming. Financially, EarthOptics raised a $10.3M A round to scale its two existing products and to develop a moisture-mapping product.

  • Switchboard Health

    Participated · Seed · May 2024

    Switchboard Health is a Boise, ID-based creator of a high-value specialty care network and software platform that helps providers, health plans, and employers identify high-value specialty care services. Its platform lets health plans deploy a single system to improve member satisfaction, reduce costs, and provide timely access to care. The software incorporates evidence-based virtual care models from the Switchboard Network, including providers such as Heartbeat Health, Brightside Health, and Tono Health. Led by CEO Derek Baird, Switchboard plans to use new funding to continue developing its software platform and to advance implementations with health plans and value-based care providers. The company raised $6.5M in seed funding in May 2024. It is backed by investors including First Trust Capital Partners and founding investor Route 66 Ventures.

  • AccessPay

    Participated · Equity · Mar 2024

    AccessPay provides cloud-based bank connectivity and bank integration solutions that connect back-office systems to banks and enable automated flow and transformation of payment, bank statement and other financial data. The platform targets finance and treasury teams, helping them optimize operations through automated payments and data exchanges. AccessPay is led by CEO Anish Kapoor and is based in Manchester, UK. The company has secured a majority investment from Accel-KKR in 2026. Proceeds from that investment are intended to fund new product development and strategic acquisitions. No revenue, user, or valuation figures were disclosed in the report.

  • Joon

    Participated · Equity · Dec 2023

    Joon Care is a Seattle teletherapy startup that delivers online therapy sessions and digital mental-health tools for patients ages 13–24, addressing anxiety, depression, disordered eating, sexual and gender identity, academic issues, and other challenges. The platform supports therapists with evidence-based care strategies and patient assessments to track progress, and Joon cites internal research showing measurable success. Since launching in 2019 as a Pioneer Square Labs spinout, the company has grown to more than 20 employees and nearly 100 therapists and now treats patients in Washington, Oregon, California, Texas, New York, Pennsylvania and Delaware. Over the past year it added eight in-network insurance plans, partnered with the City of Seattle to provide free care via human services referrals, and became a provider on the Valorant Health platform. Joon estimates 1.6 million teens and young people need care and is focusing on reaching parents and guardians through increased marketing and additional partnerships. The company is not profitable but says the new funding will extend operations while it scales access and outreach. Joon Care provides an evidence-based, mobile and personalized teletherapy service designed specifically for teens and young adults. The platform matches clients with licensed clinicians after an initial consultation and delivers a personalized treatment roadmap outlining the evidence-based skills covered in care. Treatment includes scheduled one-on-one teletherapy sessions with a dedicated therapist plus access to app-based skill-building resources. Clinical leadership, led by co-founder and Chief Psychologist Dr. Amy Mezulis, supervises all care provided. The service is powered by a purpose-built mobile app and therapist platform focused on anxiety, depression, stress and related conditions. The company is led by CEO Josh Herst and spun out of Pioneer Square Labs in April 2020 under the initial name UpLift.

Team