Nucleus Capital
Kleine Hamburger Straße 16, Berlin, 10117, Germany
Overview
Nucleus Capital is a new venture capital firm supporting purpose-driven founders. We profoundly believe that entrepreneurial innovation is necessary to tackle global threats to human and planetary health. We partner with entrepreneurs at the nucleus of their journey, investing at the Pre/Seed stage and are focussed on Synthetic & Computational Biology, Food- and Climate Technology.
- Total investments
- 19
- Lead investments
- 4
- Investments · 12mo
- 3
- Active investors
- 2
Sector focus
- Biotechnology
- Nutrition
- Software
- Sustainability
- Venture Capital
Investment portfolio
- Triple Bio
Participated · Seed · May 2026
Triple Bio is developing next-generation lipid ingredients for livestock feed aimed at improving feed efficiency, increasing milk production and lowering enteric methane emissions. The company’s technology focuses on lipid-based feed additives designed to simultaneously target yield and methane reduction. Its founding team combines expertise in microbiology, animal science, dairy and industrial biotechnology. Triple Bio recently raised a €1.5M pre-seed round from Marble, Nucleus Capital, Positron and Climate Club to advance development. The startup is tied to the Leiden region and is using early backing to accelerate its progress.
- Telura
Participated · Seed · Mar 2026
Founded in 2025 by Philipp Engelkamp and Andrew Welling, Telura is building an electric-impulse drilling system that fractures rock with high-voltage pulses rather than mechanical grinding. This approach promises to cut drilling time and costs, addressing the primary bottleneck—drill-bit wear—when accessing 5–20 km-deep geothermal reservoirs. The technology stems from more than twenty years of research at leading German technical universities and has already demonstrated efficient granite breakage in tests. Telura’s system integrates with existing drilling rigs, allowing for faster field deployment and compatibility with current industry workflows. The company plans to enter the market in 2026 and has a validation agreement with SPRIND to accelerate commercialization. Telura positions geothermal as a 24/7 baseload energy source critical for Europe’s looming power shortfall driven by AI and electrification. To date, the startup has secured €4 million in pre-Seed funding to advance engineering and scale its prototype toward field-ready systems.
- Bindbridge
Participated · Seed · Mar 2026
Bindbridge develops BRIDGE, a machine-learning and computational-chemistry platform that proposes molecular glues capable of binding target proteins in weeds, pests, and pathogens and recruiting cellular degradation machinery. By inducing targeted protein degradation, the company aims to create herbicides, insecticides, and fungicides with new modes of action that can overcome rising resistance and reduce environmental impact. The approach seeks to open previously inaccessible chemical space and shorten the decade-long discovery cycle typical in crop protection. Founded in March 2025 by Dr George Crane, Dr Alex Campbell, and Dr Simeon Spasov, the eight-person team blends ML engineers, plant biologists, chemists, and ag specialists. Near-term plans include lab testing of its first agricultural molecular glues and co-development projects with agrochemical partners over the next 12 months. The company positions its IP-first model to tap billion-dollar markets for sustainable agriculture, addressing UN-estimated crop losses of up to 40% annually. A recent £2.8 m seed round provides the capital to advance validation and partnership activities.
- ScienceMachine
Led · Seed · Jul 2025
ScienceMachine builds Sam, a fully autonomous AI agent that automates the entire data-analysis pipeline for biotech and pharmaceutical research. Sam integrates with existing databases and lab workflows to continuously process experimental data, handling tasks from data cleaning and exploratory analysis to visualization without manual intervention. The company says Sam produces the output that would normally require a team of data scientists, accelerating research cycles and reducing costs. Early customers report results a third of the time, at a fraction of the price, and of a higher quality than they could have achieved on their own, and one month after launch ScienceMachine already has multiple contracts and a fast-growing inbound-driven pipeline. ScienceMachine claims to have delivered production-grade AI automation and will use new funding to support product development and hiring, particularly in sales and pharma partnerships. The company plans to expand its customer base from biotech startups into larger companies where annual contract values are higher and scalable data automation is needed.
- AtmoCooling
Led · Seed · Mar 2025
AtmoCooling develops a proprietary seawater evaporative cooling system that lowers ambient temperatures to create optimized microclimates for agriculture and sustainable development. The system leverages brine and seawater instead of freshwater, offering a scalable, sustainable alternative to traditional cooling methods and reducing heat stress on crops, infrastructure, and communities. The company is advancing pilot deployments in key arid regions and expanding partnerships with researchers, agricultural producers, and sustainability innovators. Led by CEO Paul Mahacek and headquartered in Seattle, WA, AtmoCooling intends to use recent funding to expand operations and grow its business reach. The article does not disclose revenue or user metrics.